AutismKB 2.0

Annotation Details for MTF1


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Basic Information Top
Gene Symbol:MTF1 ( MGC23036,MTF-1,ZRF )
Gene Full Name: metal-regulatory transcription factor 1
Band: 1p34.3
Quick LinksEntrez ID:4520; OMIM: 600172; Uniprot ID:MTF1_HUMAN; ENSEMBL ID: ENSG00000188786; HGNC ID: 7428
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634TAS-nucleus3208749
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO ID Evidence Qualifier GO_term References
GO:0000978IDA-RNA polymerase II core promoter proximal region sequence-specific DNA binding9582278
GO:0000979IEA-RNA polymerase II core promoter sequence-specific DNA binding-
GO:0001047IDA-core promoter binding15735762
GO:0001077IDA-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding9582278
GO:0003677TAS-DNA binding8065932
GO:0003700TAS-transcription factor activity, sequence-specific DNA binding3208749
GO:0003713TAS-transcription coactivator activity3208749
GO:0005515IPI-protein binding16189514
GO:0035035IEA-histone acetyltransferase binding-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0006357TAS-regulation of transcription from RNA polymerase II promoter3208749
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0006979IEA-response to oxidative stress-
GO:0010038TAS-response to metal ion-
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter9582278
GO:0046686IEA-response to cadmium ion-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MTF1CREBBP11062018458062 Affinity Capture-Western
MTF1CREBBP10777718458062 Affinity Capture-Western
MTF1EP30011062018458062 Affinity Capture-Western
MTF1EP30010834718458062 Affinity Capture-Western
AP1M1MTF111062016189514 Two-hybrid
AP1M1MTF111442116189514 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:101786
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-020424-1'