Gene Symbol:	MUC1 ( CD227,EMA,H23AG,KL-6,MAM6,PEM,PEMT,PUM )
Gene Full Name:	mucin 1, cell surface associated
Band:	1q22
Quick Links	Entrez ID:4582; OMIM: 158340; Uniprot ID:MUC1_HUMAN; ENSEMBL ID: ENSG00000185499; HGNC ID: 7508
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0000790	IDA	-	nuclear chromatin	15710329
GO:0005615	IDA	-	extracellular space	16502470
GO:0005796	TAS	-	Golgi lumen	-
GO:0005886	TAS	-	plasma membrane	-
GO:0005887	TAS	-	integral component of plasma membrane	1697589
GO:0016324	IEA	-	apical plasma membrane	-
GO:0031982	IDA	-	vesicle	19190083
GO:0070062	IDA	-	extracellular exosome	15326289

GO ID	Evidence	Qualifier	GO_term	References
GO:0000978	IDA	-	RNA polymerase II core promoter proximal region sequence-specific DNA binding	15710329
GO:0002039	IPI	-	p53 binding	15710329
GO:0003712	IDA	-	transcription cofactor activity	15710329
GO:0005515	IPI	-	protein binding	16888623

GO ID	Evidence	Qualifier	GO_term	References
GO:0002223	TAS	-	stimulatory C-type lectin receptor signaling pathway	-
GO:0006977	IDA	-	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	15710329
GO:0006978	IDA	-	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	15710329
GO:0010944	IDA	-	negative regulation of transcription by competitive promoter binding	15710329
GO:0016266	TAS	-	O-glycan processing	-
GO:0033629	IDA	-	negative regulation of cell adhesion mediated by integrin	7698991
GO:0036003	IDA	-	positive regulation of transcription from RNA polymerase II promoter in response to stress	15710329
GO:0043618	IDA	-	regulation of transcription from RNA polymerase II promoter in response to stress	15710329
GO:0090240	IDA	-	positive regulation of histone H4 acetylation	15710329
GO:1902166	IDA	-	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	15710329

Gene Symbol	Interactant	Interaction ID	References	Description
MUC1	APC	106821	15020226	Affinity Capture-Western
MUC1	APC	110669	15020226	Affinity Capture-Western
MUC1	CTNNB1	107880	9139698 9819408 11152665 11483589 11877440 12618757 12750561	Affinity Capture-Western; Reconstituted Complex
MUC1	CTNNB1	110669	9139698 9819408 11152665 11483589 11877440 12618757 12750561	Affinity Capture-Western; Reconstituted Complex
MUC1	CTNND1	107881	11181067	Affinity Capture-Western; Co-localization; Reconstituted Complex
MUC1	CTNND1	110669	11181067	Affinity Capture-Western; Co-localization; Reconstituted Complex
MUC1	EGFR	110669	11278868 11483589 16983337	Affinity Capture-Western; Biochemical Activity
MUC1	EGFR	108276	11278868 11483589 16983337	Affinity Capture-Western; Biochemical Activity
MUC1	ERBB2	108376	11278868 12939402	Affinity Capture-Western; Co-localization
MUC1	ERBB2	110669	11278868 12939402	Affinity Capture-Western; Co-localization
MUC1	ERBB3	110669	11278868	Affinity Capture-Western
MUC1	ERBB3	108377	11278868	Affinity Capture-Western
MUC1	ERBB4	110669	11278868	Affinity Capture-Western
MUC1	ERBB4	108378	11278868	Affinity Capture-Western
MUC1	ESR1	108403	16427018	Affinity Capture-Western; Reconstituted Complex
MUC1	ESR1	110669	16427018	Affinity Capture-Western; Reconstituted Complex
MUC1	GRB2	109142	7664271 20936779	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MUC1	GRB2	110669	7664271 20936779	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MUC1	GSK3B	109187	9819408 11152665	Affinity Capture-Western; Reconstituted Complex
MUC1	GSK3B	110669	9819408 11152665	Affinity Capture-Western; Reconstituted Complex
MUC1	JUP	109931	12939402	Affinity Capture-Western; Co-localization
MUC1	JUP	110669	12939402	Affinity Capture-Western; Co-localization
MUC1	LYN	110245	12750561	Affinity Capture-Western; Reconstituted Complex
MUC1	LYN	110669	12750561	Affinity Capture-Western; Reconstituted Complex
SOS1	MUC1	112537	7664271 11278868	Affinity Capture-Western
SOS1	MUC1	110669	7664271 11278868	Affinity Capture-Western
SRC	MUC1	112592	11152665 11483589	Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
SRC	MUC1	110669	11152665 11483589	Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
PRKCD	MUC1	111566	11877440	Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
PRKCD	MUC1	110669	11877440	Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
GALNT12	MUC1	122816	12135769	Biochemical Activity
GALNT12	MUC1	110669	12135769	Biochemical Activity
GALNT4	MUC1	114240	12754287	Biochemical Activity
GALNT4	MUC1	110669	12754287	Biochemical Activity

AutismKB 2.0

Annotation Details for MUC1

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Non-syndromic Genes

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