AutismKB 2.0

Annotation Details for MVK


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Basic Information Top
Gene Symbol:MVK ( FLJ96772,LRBP,MK,MVLK )
Gene Full Name: mevalonate kinase
Band: 12q24.11
Quick LinksEntrez ID:4598; OMIM: 251170; Uniprot ID:KIME_HUMAN; ENSEMBL ID: ENSG00000110921; HGNC ID: 7530
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005777IDANOTperoxisome14730012
GO:0005829IDA-cytosol14730012
GO:0005829TAS-cytosol-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0004496IDA-mevalonate kinase activity1377680
GO:0004496IMP-mevalonate kinase activity10369261
GO:0004496TAS-mevalonate kinase activity-
GO:0005515IPI-protein binding21044950
GO:0005524IEA-ATP binding-
GO:0042802IPI-identical protein binding16189514
GO ID Evidence Qualifier GO_term References
GO:0006695IDA-cholesterol biosynthetic process1377680
GO:0006695TAS-cholesterol biosynthetic process-
GO:0008299IDA-isoprenoid biosynthetic process14680974
GO:0016310IEA-phosphorylation-
GO:0019287IBA-isopentenyl diphosphate biosynthetic process, mevalonate pathway-
GO:0019287IEA-isopentenyl diphosphate biosynthetic process, mevalonate pathway-
GO:0045540TAS-regulation of cholesterol biosynthetic process-
GO:0050728IMP-negative regulation of inflammatory response16732551
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MVKEWSR110843116189514 Two-hybrid
MVKEWSR111068316189514 Two-hybrid
MVKMVK11068316189514 Affinity Capture-Western; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:107624
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-041114-37'