AutismKB 2.0

Annotation Details for MYB


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Basic Information Top
Gene Symbol:MYB ( Cmyb,c-myb,c-myb_CDS,efg )
Gene Full Name: v-myb myeloblastosis viral oncogene homolog (avian)
Band: 6q23.3
Quick LinksEntrez ID:4602; OMIM: 189990; Uniprot ID:MYB_HUMAN; ENSEMBL ID: ENSG00000118513; HGNC ID: 7545
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IBA-nucleus-
GO:0016363NAS-nuclear matrix3014652
GO ID Evidence Qualifier GO_term References
GO:0000978IDA-RNA polymerase II core promoter proximal region sequence-specific DNA binding7987850
GO:0000981IBA-RNA polymerase II transcription factor activity, sequence-specific DNA binding-
GO:0001077IC-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-
GO:0001135IBA-transcription factor activity, RNA polymerase II transcription factor recruiting-
GO:0005515IPI-protein binding18093978
GO ID Evidence Qualifier GO_term References
GO:0000122IMP-negative regulation of transcription from RNA polymerase II promoter20531406
GO:0000278IBA-mitotic cell cycle-
GO:0001666IEA-response to hypoxia-
GO:0006338IMP-chromatin remodeling20484083
GO:0006355NAS-regulation of transcription, DNA-templated2189102
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0032967IEA-positive regulation of collagen biosynthetic process-
GO:0043525IEA-positive regulation of neuron apoptotic process-
GO:0045624IMP-positive regulation of T-helper cell differentiation20484083
GO:0045892IMP-negative regulation of transcription, DNA-templated20531406
GO:0045893IMP-positive regulation of transcription, DNA-templated20484083
GO:0045893NAS-positive regulation of transcription, DNA-templated2189102
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter10233885
GO:0045944IMP-positive regulation of transcription from RNA polymerase II promoter20531406
GO:0048661IEA-positive regulation of smooth muscle cell proliferation-
GO:0051571IMP-positive regulation of histone H3-K4 methylation20484083
GO:0051574IMP-positive regulation of histone H3-K9 methylation20484083
GO:0060252IEA-positive regulation of glial cell proliferation-
GO:0070301IEA-cellular response to hydrogen peroxide-
GO:0071300IEA-cellular response to retinoic acid-
GO:0071636IEA-positive regulation of transforming growth factor beta production-
GO:1904899IEA-positive regulation of hepatic stellate cell proliferation-
GO:2000491IEA-positive regulation of hepatic stellate cell activation-
GO:2000845IEA-positive regulation of testosterone secretion-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MYBPARP111068718945670 Affinity Capture-Western
MYBPARP110665218945670 Affinity Capture-Western
MYBCEBPB11068711792321 Co-crystal Structure
MYBCEBPB10748011792321 Co-crystal Structure
MYBCEBPE11068710233885 Reconstituted Complex
MYBCEBPE10748210233885 Reconstituted Complex
MYBCREBBP11068711073948 11423988 12196545 14761981 16055500 Affinity Capture-Western; Biochemical Activity; Co-crystal Structure; Phenotypic Enhancement; Reconstituted Complex
MYBCREBBP10777711073948 11423988 12196545 14761981 16055500 Affinity Capture-Western; Biochemical Activity; Co-crystal Structure; Phenotypic Enhancement; Reconstituted Complex
MYBEP30010834711585920 Reconstituted Complex
MYBEP30011068711585920 Reconstituted Complex
MYBHLF11068720211142 Two-hybrid
MYBHLF10937620211142 Two-hybrid
MYBMAF1102699566892 Reconstituted Complex; Two-hybrid
MYBMAF1106879566892 Reconstituted Complex; Two-hybrid
MYBMEN111068720093773 Affinity Capture-Western
MYBMEN111038420093773 Affinity Capture-Western
MYBMLL11068720093773 Affinity Capture-Western
MYBMLL11044320093773 Affinity Capture-Western
SND1MYB1179748756344 Reconstituted Complex; Two-hybrid
SND1MYB1106878756344 Reconstituted Complex; Two-hybrid
SMARCA2MYB11247910619021 Reconstituted Complex
SMARCA2MYB11068710619021 Reconstituted Complex
NCLMYB11068710660576 Affinity Capture-Western
NCLMYB11077110660576 Affinity Capture-Western
ZMYND11MYB11598911244510 Reconstituted Complex; Two-hybrid
ZMYND11MYB11068711244510 Reconstituted Complex; Two-hybrid
SUMO1MYB11318811779867 Affinity Capture-Western
SUMO1MYB11068711779867 Affinity Capture-Western
UBE2IMYB11317711779867 Two-hybrid
UBE2IMYB11068711779867 Two-hybrid
PAX5MYB11068711781241 Affinity Capture-Western
PAX5MYB11111311781241 Affinity Capture-Western
TTF2MYB11403612927788 Two-hybrid
TTF2MYB11068712927788 Two-hybrid
TRIM28MYB11545714761981 Affinity Capture-Western; Reconstituted Complex
TRIM28MYB11068714761981 Affinity Capture-Western; Reconstituted Complex
SIN3AMYB11743914761981 Affinity Capture-Western; Reconstituted Complex
SIN3AMYB11068714761981 Affinity Capture-Western; Reconstituted Complex
SKIMYB11238814761981 Affinity Capture-Western; Reconstituted Complex
SKIMYB11068714761981 Affinity Capture-Western; Reconstituted Complex
NCOR1MYB11497314761981 Affinity Capture-Western; Reconstituted Complex
NCOR1MYB11068714761981 Affinity Capture-Western; Reconstituted Complex
UBCMYB11316415082531 Affinity Capture-Western
UBCMYB11068715082531 Affinity Capture-Western
NLKMYB11968515082531 16055500 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
NLKMYB11068715082531 16055500 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
HIPK2MYB11881515082531 16055500 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
HIPK2MYB11068715082531 16055500 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
PMLMYB11138415194430 Affinity Capture-Western; Reconstituted Complex
PMLMYB11068715194430 Affinity Capture-Western; Reconstituted Complex
SUMO2MYB11249717077080 Affinity Capture-Western
SUMO2MYB11068717077080 Affinity Capture-Western
FBXW7MYB12058118765672 Affinity Capture-Western; Biochemical Activity
FBXW7MYB11068718765672 Affinity Capture-Western; Biochemical Activity
WDR5MYB11627220093773 Affinity Capture-Western
WDR5MYB11068720093773 Affinity Capture-Western
RBBP5MYB11068720093773 Affinity Capture-Western
RBBP5MYB11186420093773 Affinity Capture-Western
ASH2LMYB11452820093773 Affinity Capture-Western
ASH2LMYB11068720093773 Affinity Capture-Western
SP100MYB11255520211142 Two-hybrid
SP100MYB11068720211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
MYBrs1013891, rs3819409 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:97249
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-991110-14'