AutismKB 2.0

Annotation Details for GADD45B


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Basic Information Top
Gene Symbol:GADD45B ( DKFZp566B133,GADD45BETA,MYD118 )
Gene Full Name: growth arrest and DNA-damage-inducible, beta
Band: 19p13.3
Quick LinksEntrez ID:4616; OMIM: 604948; Uniprot ID:GA45B_HUMAN; ENSEMBL ID: ENSG00000099860; HGNC ID: 4096
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus9827804
GO:0005737IDA-cytoplasm9827804
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding12052864
GO ID Evidence Qualifier GO_term References
GO:0000185IDA-activation of MAPKKK activity9827804
GO:0000186IEA-activation of MAPKK activity-
GO:0006469IEA-negative regulation of protein kinase activity-
GO:0006915IEA-apoptotic process-
GO:0006950IEA-response to stress-
GO:0007275IEA-multicellular organism development-
GO:0030154IEA-cell differentiation-
GO:0043065IDA-positive regulation of apoptotic process9827804
GO:0046330IDA-positive regulation of JNK cascade9827804
GO:0051726IBA-regulation of cell cycle-
GO:1900745IDA-positive regulation of p38MAPK cascade9827804
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GADD45BCCNB111070112124778 Reconstituted Complex
GADD45BCCNB110733212124778 Reconstituted Complex
GADD45BCDK111070112124778 Reconstituted Complex
GADD45BCDK110742012124778 Reconstituted Complex
GADD45BGADD45A10801411498536 Affinity Capture-Western
GADD45BGADD45A11070111498536 Affinity Capture-Western
GADD45BMAP3K41103809827804 16256071 Affinity Capture-Western; Two-hybrid
GADD45BMAP3K41107019827804 16256071 Affinity Capture-Western; Two-hybrid
GADD45BMAP3K511070114743220 Affinity Capture-Western; Reconstituted Complex
GADD45BMAP3K511038114743220 Affinity Capture-Western; Reconstituted Complex
GADD45GIP1GADD45B12472112716909 Affinity Capture-Western; Reconstituted Complex
GADD45GIP1GADD45B11070112716909 Affinity Capture-Western; Reconstituted Complex
MAP2K7GADD45B11159514743220 Affinity Capture-Western; Reconstituted Complex
MAP2K7GADD45B11070114743220 Affinity Capture-Western; Reconstituted Complex
Gene Symbol Interactant Interaction ID References Description
GADD45BCCNB118337912124778 Cyclin B1 interacts with Gadd45b. This interaction was modeled on a demonstrated interaction between human Cyclin B1 and Gadd45b from an unspecified species.
GADD45BCDK118337612124778 Cdk1 interacts with Gadd45b. This interaction was modeled on a demonstrated interaction between human Cdk1 and Gadd45b from an unspecified species.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:107776
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-1971'