AutismKB 2.0

Annotation Details for MYH6


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Basic Information Top
Gene Symbol:MYH6 ( ASD3,CMD1EE,CMH14,MYHC,MYHCA,alpha-MHC )
Gene Full Name: myosin, heavy chain 6, cardiac muscle, alpha
Band: 14q11.2
Quick LinksEntrez ID:4624; OMIM: 160710; Uniprot ID:MYH6_HUMAN; ENSEMBL ID: ENSG00000197616; HGNC ID: 7576
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001725IEA-stress fiber-
GO:0005829TAS-cytosol-
GO:0005859TAS-muscle myosin complex1776652
GO:0016459TAS-myosin complex12933792
GO:0030016ISS-myofibril-
GO:0030017TAS-sarcomere12933792
GO:0030018IEA-Z disc-
GO:0032982IEA-myosin filament-
GO ID Evidence Qualifier GO_term References
GO:0000146IDA-microfilament motor activity15621050
GO:0000146ISS-microfilament motor activity-
GO:0003779IEA-actin binding-
GO:0005516IEA-calmodulin binding-
GO:0005524IEA-ATP binding-
GO:0016887IDA-ATPase activity15621050
GO:0017018TAS-myosin phosphatase activity-
GO:0019901IPI-protein kinase binding18029400
GO:0030898IMP-actin-dependent ATPase activity16088376
GO ID Evidence Qualifier GO_term References
GO:0001701ISS-in utero embryonic development-
GO:0002026IDA-regulation of the force of heart contraction15621050
GO:0002026ISS-regulation of the force of heart contraction-
GO:0002027IDA-regulation of heart rate15621050
GO:0006470IEA-protein dephosphorylation-
GO:0006936IDA-muscle contraction15621050
GO:0006941IMP-striated muscle contraction15621050
GO:0006941ISS-striated muscle contraction-
GO:0007512IMP-adult heart development15735645
GO:0007522ISS-visceral muscle development-
GO:0008016ISS-regulation of heart contraction-
GO:0008217ISS-regulation of blood pressure-
GO:0014898IEA-cardiac muscle hypertrophy in response to stress-
GO:0030049IMP-muscle filament sliding16088376
GO:0030049TAS-muscle filament sliding-
GO:0030239ISS-myofibril assembly-
GO:0030509IEA-BMP signaling pathway-
GO:0043462ISS-regulation of ATPase activity-
GO:0045214ISS-sarcomere organization-
GO:0046034IDA-ATP metabolic process15621050
GO:0048739ISS-cardiac muscle fiber development-
GO:0055009IMP-atrial cardiac muscle tissue morphogenesis15735645
GO:0055010IMP-ventricular cardiac muscle tissue morphogenesis11815426
GO:0060048ISS-cardiac muscle contraction9884344
GO:0060070IEA-canonical Wnt signaling pathway-
GO:0060420IEA-regulation of heart growth-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:97255
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-031112-1'