AutismKB 2.0

Annotation Details for ZFHX3


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Basic Information Top
Gene Symbol:ZFHX3 ( ATBF1,ATBT,ZNF927 )
Gene Full Name: zinc finger homeobox 3
Band: 16q22.2-q22.3
Quick LinksEntrez ID:463; OMIM: 104155; Uniprot ID:ZFHX3_HUMAN; ENSEMBL ID: ENSG00000140836; HGNC ID: 777
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus20599712
GO:0005634TAS-nucleus1719379
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005667IDA-transcription factor complex10318867
GO:0005737IDA-cytoplasm20599712
GO:0016604IDA-nuclear body24651376
GO ID Evidence Qualifier GO_term References
GO:0001046ISS-core promoter sequence-specific DNA binding-
GO:0003700NAS-transcription factor activity, sequence-specific DNA binding1719379
GO:0003705TAS-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding1719379
GO:0005515IPI-protein binding20599712
GO:0008270IEA-zinc ion binding-
GO:0019899IPI-enzyme binding14715251
GO:0046983IEA-protein dimerization activity-
GO ID Evidence Qualifier GO_term References
GO:0000122IGI-negative regulation of transcription from RNA polymerase II promoter10318867
GO:0006355TAS-regulation of transcription, DNA-templated1719379
GO:0006366TAS-transcription from RNA polymerase II promoter1719379
GO:0007050IEA-cell cycle arrest-
GO:0007420IEA-brain development-
GO:0007517IEA-muscle organ development-
GO:0032922ISS-circadian regulation of gene expression-
GO:0045664IEA-regulation of neuron differentiation-
GO:0045893IDA-positive regulation of transcription, DNA-templated20599712
GO:0071559IDA-response to transforming growth factor beta20599712
GO:1904059ISS-regulation of locomotor rhythm-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PRPF40AZFHX31069549171351 Far Western
PRPF40AZFHX31207929171351 Far Western
NINLZFHX310695416189514 Two-hybrid
NINLZFHX311663016189514 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:99948
  • Data Attributes: MGI curated and HomoloGene calculated
No data