AutismKB 2.0

Annotation Details for MYL2


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Basic Information Top
Gene Symbol:MYL2 ( CMH10,DKFZp779C0562,MLC2 )
Gene Full Name: myosin, light chain 2, regulatory, cardiac, slow
Band: 12q24.11
Quick LinksEntrez ID:4633; OMIM: 160781; Uniprot ID:MLRV_HUMAN; ENSEMBL ID: ENSG00000111245; HGNC ID: 7583
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0005856IDA-cytoskeleton17043135
GO:0015629IDAcolocalizes_withactin cytoskeleton17043135
GO:0016459TAS-myosin complex11102452
GO:0030016NAS-myofibril8287067
GO:0030017TAS-sarcomere16754800
GO:0031672IEA-A band-
GO:0097512IDA-cardiac myofibril25771144
GO ID Evidence Qualifier GO_term References
GO:0003785IDA-actin monomer binding9180271
GO:0005509IDA-calcium ion binding11102452
GO:0005515IPI-protein binding11773029
GO:0008307NAS-structural constituent of muscle17885681
GO:0032036NAS-myosin heavy chain binding8287067
GO ID Evidence Qualifier GO_term References
GO:0002026ISS-regulation of the force of heart contraction-
GO:0006942TAS-regulation of striated muscle contraction8673105
GO:0007507ISS-heart development-
GO:0009791IEA-post-embryonic development-
GO:0030049TAS-muscle filament sliding-
GO:0030308IMP-negative regulation of cell growth15824735
GO:0042694IEA-muscle cell fate specification-
GO:0048747IEA-muscle fiber development-
GO:0055003ISS-cardiac myofibril assembly-
GO:0055010IMP-ventricular cardiac muscle tissue morphogenesis8673105
GO:0060047ISS-heart contraction-
GO:0060048IEA-cardiac muscle contraction-
GO:0098735ISS-positive regulation of the force of heart contraction-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PAK2MYL211109810047984 Biochemical Activity
PAK2MYL211071710047984 Biochemical Activity
TRIM63MYL212419515967462 Two-hybrid
TRIM63MYL211071715967462 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:97272
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060331-137'