AutismKB 2.0

Annotation Details for MYO1C


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Basic Information Top
Gene Symbol:MYO1C ( FLJ23903,MMI-beta,MMIb,NMI,myr2 )
Gene Full Name: myosin IC
Band: 17p13.3
Quick LinksEntrez ID:4641; OMIM: 606538; Uniprot ID:MYO1C_HUMAN; ENSEMBL ID: ENSG00000197879; HGNC ID: 7597
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001725IDANOTstress fiber9858156
GO:0005643IEA-nuclear pore-
GO:0005654TAS-nucleoplasm-
GO:0005730IEA-nucleolus-
GO:0005737IDA-cytoplasm9858156
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane23262137
GO:0005902IDA-microvillus9858156
GO:0005903IEA-brush border-
GO:0009925IDA-basal plasma membrane9858156
GO:0016020IDA-membrane19946888
GO:0016328IDA-lateral plasma membrane9858156
GO:0016461TAS-unconventional myosin complex9119401
GO:0016604IDA-nuclear body-
GO:0031410IEA-cytoplasmic vesicle-
GO:0031941IDA-filamentous actin9858156
GO:0032587IEA-ruffle membrane-
GO:0045121IDA-membrane raft23262137
GO:0045160IEA-myosin I complex-
GO:0060171IEA-stereocilium membrane-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0000146IEA-microfilament motor activity-
GO:0005102IPI-receptor binding21402783
GO:0005515IPI-protein binding21402783
GO:0005516IEA-calmodulin binding-
GO:0005524IEA-ATP binding-
GO:0008022IEA-protein C-terminus binding-
GO:0017160IPI-Ral GTPase binding24056301
GO:0030898IEA-actin-dependent ATPase activity-
GO:0051015IEA-actin filament binding-
GO ID Evidence Qualifier GO_term References
GO:0006605IDA-protein targeting21402783
GO:0006612IDA-protein targeting to membrane21402783
GO:0030335IMP-positive regulation of cell migration21402783
GO:0030838IEA-positive regulation of actin filament polymerization-
GO:0038089IMP-positive regulation of cell migration by vascular endothelial growth factor signaling pathway23262137
GO:0038096TAS-Fc-gamma receptor signaling pathway involved in phagocytosis-
GO:0045815TAS-positive regulation of gene expression, epigenetic-
GO:0051028IEA-mRNA transport-
GO:0090314IMP-positive regulation of protein targeting to membrane23262137
GO:1900078IEA-positive regulation of cellular response to insulin stimulus-
GO:1900748IMP-positive regulation of vascular endothelial growth factor signaling pathway23262137
GO:2000810IMP-regulation of bicellular tight junction assembly21402783
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MYO1CCBL1073159367879 Two-hybrid
MYO1CEMD11072517620012 Affinity Capture-MS; Affinity Capture-Western
MYO1CEMD10832517620012 Affinity Capture-MS; Affinity Capture-Western
SMARCA5MYO1C11072516514417 Affinity Capture-Western
SMARCA5MYO1C11404516514417 Affinity Capture-Western
BAZ1BMYO1C11449716603771 Affinity Capture-Western
BAZ1BMYO1C11072516603771 Affinity Capture-Western
GIPC1MYO1C11597817353931 Affinity Capture-MS
GIPC1MYO1C11072517353931 Affinity Capture-MS
NEK6MYO1C11072517353931 Affinity Capture-MS
NEK6MYO1C11600017353931 Affinity Capture-MS
WDR8MYO1C11072517353931 Affinity Capture-MS
WDR8MYO1C11906817353931 Affinity Capture-MS
CIAO1MYO1C11072517353931 Affinity Capture-MS
CIAO1MYO1C11479117353931 Affinity Capture-MS
USP20MYO1C11072519615732 Affinity Capture-MS
USP20MYO1C11607719615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:106612
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-090429-3'