AutismKB 2.0

Annotation Details for MYO5A


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Basic Information Top
Gene Symbol:MYO5A ( GS1,MYH12,MYO5,MYR12 )
Gene Full Name: myosin VA (heavy chain 12, myoxin)
Band: 15q21.2
Quick LinksEntrez ID:4644; OMIM: 160777; Uniprot ID:MYO5A_HUMAN; ENSEMBL ID: ENSG00000197535; HGNC ID: 7602
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001726IDA-ruffle9852149
GO:0001750IEA-photoreceptor outer segment-
GO:0005737IDA-cytoplasm9852149
GO:0005764IDAcolocalizes_withlysosome24006491
GO:0005769IDAcolocalizes_withearly endosome24006491
GO:0005770IDAcolocalizes_withlate endosome24006491
GO:0005777IDAcolocalizes_withperoxisome24006491
GO:0005783IDAcolocalizes_withendoplasmic reticulum24006491
GO:0005794IEA-Golgi apparatus-
GO:0005829IDA-cytosol24006491
GO:0005882IEA-intermediate filament-
GO:0005884IDAcolocalizes_withactin filament24006491
GO:0016020IDA-membrane19946888
GO:0016461IEA-unconventional myosin complex-
GO:0030426NAS-growth cone10391919
GO:0031982IDAcolocalizes_withvesicle24006491
GO:0032433IDA-filopodium tip24006491
GO:0032593ISS-insulin-responsive compartment-
GO:0035371IEA-microtubule plus-end-
GO:0042470IEA-melanosome-
GO:0042641IEA-actomyosin-
GO:0043005NAS-neuron projection10391919
GO:0043025IEA-neuronal cell body-
GO:0055037IDAcolocalizes_withrecycling endosome24006491
GO:0070062IDA-extracellular exosome23533145
GO ID Evidence Qualifier GO_term References
GO:0000146NAS-microfilament motor activity10448864
GO:0003723IDA-RNA binding22681889
GO:0003779IEA-actin binding-
GO:0005509IEA-calcium ion binding-
GO:0005516IEA-calmodulin binding-
GO:0005524IEA-ATP binding-
GO:0017137IPI-Rab GTPase binding15357836
GO:0097718IEA-disordered domain specific binding-
GO ID Evidence Qualifier GO_term References
GO:0006810NAS-transport11980908
GO:0006887IEA-exocytosis-
GO:0006892IMP-post-Golgi vesicle-mediated transport24006491
GO:0007268IEA-chemical synaptic transmission-
GO:0007601IEA-visual perception-
GO:0016192ISS-vesicle-mediated transport-
GO:0030048NAS-actin filament-based movement10448864
GO:0030050IMP-vesicle transport along actin filament24006491
GO:0030073IEA-insulin secretion-
GO:0030318IEA-melanocyte differentiation-
GO:0031585IEA-regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity-
GO:0031987IEA-locomotion involved in locomotory behavior-
GO:0032252IEA-secretory granule localization-
GO:0032402IEA-melanosome transport-
GO:0032869ISS-cellular response to insulin stimulus-
GO:0042438IEA-melanin biosynthetic process-
GO:0042476IEA-odontogenesis-
GO:0042552IEA-myelination-
GO:0042759IEA-long-chain fatty acid biosynthetic process-
GO:0048820IEA-hair follicle maturation-
GO:0050808IEA-synapse organization-
GO:0051643IEA-endoplasmic reticulum localization-
GO:0072659ISS-protein localization to plasma membrane-
GO:1903358IMPNOTregulation of Golgi organization24006491
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SHANK2MYO5A11659810844022 Affinity Capture-Western
SHANK2MYO5A11072810844022 Affinity Capture-Western
DYNLL1MYO5A11420610844022 Affinity Capture-Western; Reconstituted Complex
DYNLL1MYO5A11072810844022 Affinity Capture-Western; Reconstituted Complex
DYNLL2MYO5A12668010844022 11546872 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
DYNLL2MYO5A11072810844022 11546872 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
DLGAP1MYO5A11466010844022 Reconstituted Complex
DLGAP1MYO5A11072810844022 Reconstituted Complex
BMFMYO5A11072811546872 Reconstituted Complex
BMFMYO5A12471611546872 Reconstituted Complex
RAB27AMYO5A11072812006666 12062444 Affinity Capture-Western; Reconstituted Complex
RAB27AMYO5A11181112006666 12062444 Affinity Capture-Western; Reconstituted Complex
MLPHMYO5A11072812062444 14730011 15059972 Affinity Capture-Western; Reconstituted Complex
MLPHMYO5A12253112062444 14730011 15059972 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:105976
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-041027-2'