AutismKB 2.0

Annotation Details for MYO5B


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Basic Information Top
Gene Symbol:MYO5B ( KIAA1119 )
Gene Full Name: myosin VB
Band: 18q
Quick LinksEntrez ID:4645; OMIM: 606540; Uniprot ID:MYO5B_HUMAN; ENSEMBL ID: ENSG00000167306; HGNC ID: 7603
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0016459IEA-myosin complex-
GO:0030659TAS-cytoplasmic vesicle membrane-
GO:0043234IDA-protein complex17462998
GO:0045179IDA-apical cortex21206382
GO:0055037ICcolocalizes_withrecycling endosome21206382
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0000146TAS-microfilament motor activity-
GO:0003779IEA-actin binding-
GO:0005515IPI-protein binding19542231
GO:0005516IEA-calmodulin binding-
GO:0005524IEA-ATP binding-
GO:0017137IPI-Rab GTPase binding17462998
GO ID Evidence Qualifier GO_term References
GO:0003091TAS-renal water homeostasis-
GO:0015031IEA-protein transport-
GO:0016192IMP-vesicle-mediated transport17462998
GO:0032439IMP-endosome localization21206382
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MYO5BCXCR211072915004234 Affinity Capture-Western
MYO5BCXCR210979315004234 Affinity Capture-Western
RAB11FIP2MYO5B11072912393859 Reconstituted Complex; Two-hybrid
RAB11FIP2MYO5B11651412393859 Reconstituted Complex; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:106598
  • Data Attributes: HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018