AutismKB 2.0

Annotation Details for MYO7A


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Basic Information Top
Gene Symbol:MYO7A ( DFNA11,DFNB2,MYOVIIA,MYU7A,NSRD2,USH1B )
Gene Full Name: myosin VIIA
Band: 11q13.5
Quick LinksEntrez ID:4647; OMIM: 276903; Uniprot ID:MYO7A_HUMAN; ENSEMBL ID: ENSG00000137474; HGNC ID: 7606
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001750IDA-photoreceptor outer segment8842737
GO:0001917IDA-photoreceptor inner segment8842737
GO:0005737IDA-cytoplasm23704327
GO:0005765IDA-lysosomal membrane16001398
GO:0005829IDA-cytosol15300860
GO:0005902IEA-microvillus-
GO:0005938IEA-cell cortex-
GO:0016324IEA-apical plasma membrane-
GO:0031477IEA-myosin VII complex-
GO:0032391IEA-photoreceptor connecting cilium-
GO:0032420IEA-stereocilium-
GO:0042470IEA-melanosome-
GO:0045202IDA-synapse8842737
GO:1990435IEA-upper tip-link density-
GO ID Evidence Qualifier GO_term References
GO:0000146IDA-microfilament motor activity21687988
GO:0005515IPI-protein binding11964381
GO:0005516IMP-calmodulin binding15300860
GO:0005524IEA-ATP binding-
GO:0019904IEA-protein domain specific binding-
GO:0030507IDA-spectrin binding23704327
GO:0030898IEA-actin-dependent ATPase activity-
GO:0042803IEA-protein homodimerization activity-
GO:0043531IEA-ADP binding-
GO:0047485IEA-protein N-terminus binding-
GO:0051015IDA-actin filament binding21687988
GO ID Evidence Qualifier GO_term References
GO:0001845IEA-phagolysosome assembly-
GO:0006886IEA-intracellular protein transport-
GO:0007040IDA-lysosome organization16001398
GO:0007601IMP-visual perception7870171
GO:0007605IMP-sensory perception of sound7870171
GO:0030048IDA-actin filament-based movement21687988
GO:0042462IC-eye photoreceptor cell development8842737
GO:0048563IEA-post-embryonic animal organ morphogenesis-
GO:0050953IMP-sensory perception of light stimulus11398101
GO:0050957IMP-equilibrioception7870171
GO:0051904IEA-pigment granule transport-
GO:0060088IEA-auditory receptor cell stereocilium organization-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MYO7ACALM110725211171103 Reconstituted Complex
MYO7ACALM111073111171103 Reconstituted Complex
MYO7ACDH111073111080149 Affinity Capture-Western
MYO7ACDH110743411080149 Affinity Capture-Western
MYO7ACTNNA111073111080149 Affinity Capture-Western
MYO7ACTNNA110787611080149 Affinity Capture-Western
MYO7ACTNNB111073111080149 Affinity Capture-Western
MYO7ACTNNB110788011080149 Affinity Capture-Western
MYO7AMAP211030511171103 Affinity Capture-Western; Reconstituted Complex
MYO7AMAP211073111171103 Affinity Capture-Western; Reconstituted Complex
MYO7AMGMT11073116226712 Affinity Capture-MS
MYO7AMGMT11041116226712 Affinity Capture-MS
PRKAR1AMYO7A11073110889203 Affinity Capture-Western; Two-hybrid
PRKAR1AMYO7A11155910889203 Affinity Capture-Western; Two-hybrid
VEZTMYO7A11073111080149 Affinity Capture-Western; Two-hybrid
VEZTMYO7A12073611080149 Affinity Capture-Western; Two-hybrid
KEAP1MYO7A11073111921171 Two-hybrid
KEAP1MYO7A11515611921171 Two-hybrid
USH1CMYO7A11073112485990 Reconstituted Complex
USH1CMYO7A11539212485990 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:104510
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-020709-1'