AutismKB 2.0

Annotation Details for ATF3


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Basic Information Top
Gene Symbol:ATF3 ( - )
Gene Full Name: activating transcription factor 3
Band: 1q32.3
Quick LinksEntrez ID:467; OMIM: 603148; Uniprot ID:ATF3_HUMAN; ENSEMBL ID: ENSG00000162772; HGNC ID: 785
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus8622660
GO:0005654TAS-nucleoplasm-
GO:0005730IDA-nucleolus-
GO:1990622IDA-CHOP-ATF3 complex8622660
GO ID Evidence Qualifier GO_term References
GO:0000976IDA-transcription regulatory region sequence-specific DNA binding24939851
GO:0000977IDA-RNA polymerase II regulatory region sequence-specific DNA binding2516827
GO:0000978IEA-RNA polymerase II core promoter proximal region sequence-specific DNA binding-
GO:0001078IEA-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-
GO:0001228IC-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-
GO:0003700IGI-transcription factor activity, sequence-specific DNA binding24939851
GO:0003714TAS-transcription corepressor activity7515060
GO:0005515IPI-protein binding10327051
GO:0042802IPI-identical protein binding18255255
GO:0042803IDA-protein homodimerization activity8622660
GO:0044212IDA-transcription regulatory region DNA binding8622660
GO:0046982IPI-protein heterodimerization activity8622660
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter8622660
GO:0006094IEA-gluconeogenesis-
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0008284IEA-positive regulation of cell proliferation-
GO:0034198IEA-cellular response to amino acid starvation-
GO:0035914IEA-skeletal muscle cell differentiation-
GO:0036499TAS-PERK-mediated unfolded protein response-
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter16300731
GO:0061394TAS-regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance14685163
GO:0070373IEA-negative regulation of ERK1 and ERK2 cascade-
GO:1903984IMP-positive regulation of TRAIL-activated apoptotic signaling pathway24939851
GO:1990440IDA-positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress24939851
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
JUNATF31069571827203 8622660 14667575 Affinity Capture-Western; Reconstituted Complex
JUNATF31099281827203 8622660 14667575 Affinity Capture-Western; Reconstituted Complex
JUNDATF31069578152431 Affinity Capture-Western; Reconstituted Complex
JUNDATF31099308152431 Affinity Capture-Western; Reconstituted Complex
DDIT3ATF31069578622660 Affinity Capture-Western; Reconstituted Complex
DDIT3ATF31080168622660 Affinity Capture-Western; Reconstituted Complex
TP53ATF311301011792711 15933712 16169070 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TP53ATF310695711792711 15933712 16169070 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD3ATF310695712718878 Affinity Capture-Western; Reconstituted Complex
SMAD3ATF311026312718878 Affinity Capture-Western; Reconstituted Complex
SMARCA4ATF310695714673171 Affinity Capture-Western
SMARCA4ATF311248114673171 Affinity Capture-Western
MDM2ATF310695715933712 Reconstituted Complex
MDM2ATF311035815933712 Reconstituted Complex
FGFR3ATF310695716169070 Two-hybrid
FGFR3ATF310855216169070 Two-hybrid
C1orf103ATF310695716169070 Two-hybrid
C1orf103ATF312090516169070 Two-hybrid
IGSF21ATF310695716169070 Two-hybrid
IGSF21ATF312439616169070 Two-hybrid
RELAATF310695716291753 Affinity Capture-Western; Reconstituted Complex
RELAATF311190216291753 Affinity Capture-Western; Reconstituted Complex
ATF4ATF310695719164757 Affinity Capture-Western
ATF4ATF310695819164757 Affinity Capture-Western
ATF2ATF310695720211142 Two-hybrid
ATF2ATF310777620211142 Two-hybrid
SS18L1ATF310695720211142 Two-hybrid
SS18L1ATF311750520211142 Two-hybrid
POLR3DATF310695720211142 Two-hybrid
POLR3DATF310712920211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:109384
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-728'