AutismKB 2.0

Annotation Details for ATIC


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Basic Information Top
Gene Symbol:ATIC ( AICAR,AICARFT,FLJ93545,IMPCHASE,PURH )
Gene Full Name: 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Band: 2q35
Quick LinksEntrez ID:471; OMIM: 601731; Uniprot ID:PUR9_HUMAN; ENSEMBL ID: ENSG00000138363; HGNC ID: 794
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005739IEA-mitochondrion-
GO:0005829TAS-cytosol-
GO:0016020IDA-membrane19946888
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0003937TAS-IMP cyclohydrolase activity-
GO:0004643TAS-phosphoribosylaminoimidazolecarboxamide formyltransferase activity-
GO:0042803IPI-protein homodimerization activity14756553
GO:0045296IDA-cadherin binding25468996
GO ID Evidence Qualifier GO_term References
GO:0003360IEA-brainstem development-
GO:0006139TAS-nucleobase-containing compound metabolic process8567683
GO:0006189IEA-'de novo' IMP biosynthetic process-
GO:0009116IEA-nucleoside metabolic process-
GO:0009168TAS-purine ribonucleoside monophosphate biosynthetic process-
GO:0010035IEA-response to inorganic substance-
GO:0021549IEA-cerebellum development-
GO:0021987IEA-cerebral cortex development-
GO:0031100IEA-animal organ regeneration-
GO:0046452IEA-dihydrofolate metabolic process-
GO:0046654IEA-tetrahydrofolate biosynthetic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CMBLATIC12638717353931 Affinity Capture-MS
CMBLATIC10696117353931 Affinity Capture-MS
ELF3ATIC10696117353931 Affinity Capture-MS
ELF3ATIC10831417353931 Affinity Capture-MS
STOMATIC10835417353931 Affinity Capture-MS
STOMATIC10696117353931 Affinity Capture-MS
JAK1ATIC10696117353931 Affinity Capture-MS
JAK1ATIC10991917353931 Affinity Capture-MS
NME2ATIC10696117353931 Affinity Capture-MS
NME2ATIC11089517353931 Affinity Capture-MS
NDUFAF1ATIC11929217353931 Affinity Capture-MS
NDUFAF1ATIC10696117353931 Affinity Capture-MS
RADILATIC12082317353931 Affinity Capture-MS
RADILATIC10696117353931 Affinity Capture-MS
SNRPAATIC10696117353931 Affinity Capture-MS
SNRPAATIC11251017353931 Affinity Capture-MS
PSTPIP1ATIC10696117353931 Affinity Capture-MS
PSTPIP1ATIC11451317353931 Affinity Capture-MS
IKBKEATIC10696117353931 Affinity Capture-MS
IKBKEATIC11500017353931 Affinity Capture-MS
HNRPDLATIC11530817353931 Affinity Capture-MS
HNRPDLATIC10696117353931 Affinity Capture-MS
EGFRATIC10696120029029 PCA
EGFRATIC10827620029029 PCA
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1351352
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-011212-4'