Gene Symbol:	ATIC ( AICAR,AICARFT,FLJ93545,IMPCHASE,PURH )
Gene Full Name:	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Band:	2q35
Quick Links	Entrez ID:471; OMIM: 601731; Uniprot ID:PUR9_HUMAN; ENSEMBL ID: ENSG00000138363; HGNC ID: 794
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0005739	IEA	-	mitochondrion	-
GO:0005829	TAS	-	cytosol	-
GO:0016020	IDA	-	membrane	19946888
GO:0070062	IDA	-	extracellular exosome	19056867

GO ID	Evidence	Qualifier	GO_term	References
GO:0003937	TAS	-	IMP cyclohydrolase activity	-
GO:0004643	TAS	-	phosphoribosylaminoimidazolecarboxamide formyltransferase activity	-
GO:0042803	IPI	-	protein homodimerization activity	14756553
GO:0045296	IDA	-	cadherin binding	25468996

GO ID	Evidence	Qualifier	GO_term	References
GO:0003360	IEA	-	brainstem development	-
GO:0006139	TAS	-	nucleobase-containing compound metabolic process	8567683
GO:0006189	IEA	-	'de novo' IMP biosynthetic process	-
GO:0009116	IEA	-	nucleoside metabolic process	-
GO:0009168	TAS	-	purine ribonucleoside monophosphate biosynthetic process	-
GO:0010035	IEA	-	response to inorganic substance	-
GO:0021549	IEA	-	cerebellum development	-
GO:0021987	IEA	-	cerebral cortex development	-
GO:0031100	IEA	-	animal organ regeneration	-
GO:0046452	IEA	-	dihydrofolate metabolic process	-
GO:0046654	IEA	-	tetrahydrofolate biosynthetic process	-

Gene Symbol	Interactant	Interaction ID	References	Description
CMBL	ATIC	126387	17353931	Affinity Capture-MS
CMBL	ATIC	106961	17353931	Affinity Capture-MS
ELF3	ATIC	106961	17353931	Affinity Capture-MS
ELF3	ATIC	108314	17353931	Affinity Capture-MS
STOM	ATIC	108354	17353931	Affinity Capture-MS
STOM	ATIC	106961	17353931	Affinity Capture-MS
JAK1	ATIC	106961	17353931	Affinity Capture-MS
JAK1	ATIC	109919	17353931	Affinity Capture-MS
NME2	ATIC	106961	17353931	Affinity Capture-MS
NME2	ATIC	110895	17353931	Affinity Capture-MS
NDUFAF1	ATIC	119292	17353931	Affinity Capture-MS
NDUFAF1	ATIC	106961	17353931	Affinity Capture-MS
RADIL	ATIC	120823	17353931	Affinity Capture-MS
RADIL	ATIC	106961	17353931	Affinity Capture-MS
SNRPA	ATIC	106961	17353931	Affinity Capture-MS
SNRPA	ATIC	112510	17353931	Affinity Capture-MS
PSTPIP1	ATIC	106961	17353931	Affinity Capture-MS
PSTPIP1	ATIC	114513	17353931	Affinity Capture-MS
IKBKE	ATIC	106961	17353931	Affinity Capture-MS
IKBKE	ATIC	115000	17353931	Affinity Capture-MS
HNRPDL	ATIC	115308	17353931	Affinity Capture-MS
HNRPDL	ATIC	106961	17353931	Affinity Capture-MS
EGFR	ATIC	106961	20029029	PCA
EGFR	ATIC	108276	20029029	PCA

AutismKB 2.0

Annotation Details for ATIC