Annotation Details for NEDD8


Gene Symbol: | NEDD8 ( FLJ43224,MGC104393,MGC125896,MGC125897,Nedd-8 ) |
---|---|
Gene Full Name: | neural precursor cell expressed, developmentally down-regulated 8 |
Band: | 14q12 |
Quick Links | Entrez ID:4738; OMIM: 603171; Uniprot ID:NEDD8_HUMAN; ENSEMBL ID: ENSG00000129559; HGNC ID: 7732 |
Relate to Another Database: | SFARIGene; denovo-db |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0005634 | TAS | - | nucleus | 9353319 |
GO:0005654 | TAS | - | nucleoplasm | - |
GO:0005829 | TAS | - | cytosol | - |
GO:0070062 | IDA | - | extracellular exosome | 20458337 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0005515 | IPI | - | protein binding | 15988528 |
GO:0031625 | IPI | - | ubiquitin protein ligase binding | 15694336 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0006357 | IEA | - | regulation of transcription from RNA polymerase II promoter | - |
GO:0006464 | TAS | - | cellular protein modification process | 9694792 |
GO:0006508 | TAS | - | proteolysis | 9694792 |
GO:0006511 | TAS | - | ubiquitin-dependent protein catabolic process | 9353319 |
GO:0006879 | TAS | - | cellular iron ion homeostasis | - |
GO:0007179 | TAS | - | transforming growth factor beta receptor signaling pathway | - |
GO:0008104 | IEA | - | protein localization | - |
GO:0009653 | TAS | - | anatomical structure morphogenesis | 9694792 |
GO:0014070 | IEA | - | response to organic cyclic compound | - |
GO:0016567 | TAS | - | protein ubiquitination | - |
GO:0016579 | TAS | - | protein deubiquitination | - |
GO:0043687 | TAS | - | post-translational protein modification | - |
GO:0045116 | IDA | - | protein neddylation | 10500095 |
Gene Symbol | Interactant | Interaction ID | References | Description |
---|---|---|---|---|
NEDD8 | PARP1 | 106652 | 16620772 | Affinity Capture-MS |
NEDD8 | PARP1 | 110815 | 16620772 | Affinity Capture-MS |
NEDD8 | AHR | 106699 | 12215427 | Affinity Capture-Western; Reconstituted Complex |
NEDD8 | AHR | 110815 | 12215427 | Affinity Capture-Western; Reconstituted Complex |
NEDD8 | CDK2 | 110815 | 17353931 | Affinity Capture-MS |
NEDD8 | CDK2 | 107452 | 17353931 | Affinity Capture-MS |
NEDD8 | DDB1 | 110815 | 16964240 | Affinity Capture-MS |
NEDD8 | DDB1 | 108009 | 16964240 | Affinity Capture-MS |
NEDD8 | EGFR | 110815 | 16735510 | Affinity Capture-Western |
NEDD8 | EGFR | 108276 | 16735510 | Affinity Capture-Western |
UCHL3 | NEDD8 | 113194 | 9790970 | Reconstituted Complex; Two-hybrid |
UCHL3 | NEDD8 | 110815 | 9790970 | Reconstituted Complex; Two-hybrid |
UBE2M | NEDD8 | 110815 | 10207026 16620772 16735510 | Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Reconstituted Complex |
UBE2M | NEDD8 | 114504 | 10207026 16620772 16735510 | Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Reconstituted Complex |
UBA3 | NEDD8 | 110815 | 10207026 16620772 | Affinity Capture-MS; Biochemical Activity; Reconstituted Complex |
UBA3 | NEDD8 | 114503 | 10207026 16620772 | Affinity Capture-MS; Biochemical Activity; Reconstituted Complex |
UBA2 | NEDD8 | 115365 | 10217437 | Reconstituted Complex |
UBA2 | NEDD8 | 110815 | 10217437 | Reconstituted Complex |
NUB1 | NEDD8 | 110815 | 11585840 14757770 | Affinity Capture-Western; Reconstituted Complex |
NUB1 | NEDD8 | 119670 | 11585840 14757770 | Affinity Capture-Western; Reconstituted Complex |
PSMD4 | NEDD8 | 110815 | 11585840 | Reconstituted Complex |
PSMD4 | NEDD8 | 111683 | 11585840 | Reconstituted Complex |
CUL4A | NEDD8 | 114029 | 12481031 16620772 16964240 | Affinity Capture-MS |
CUL4A | NEDD8 | 110815 | 12481031 16620772 16964240 | Affinity Capture-MS |
RBX1 | NEDD8 | 115301 | 12481031 | Affinity Capture-MS |
RBX1 | NEDD8 | 110815 | 12481031 | Affinity Capture-MS |
SENP8 | NEDD8 | 125819 | 12759363 | Reconstituted Complex |
SENP8 | NEDD8 | 110815 | 12759363 | Reconstituted Complex |
UCHL1 | NEDD8 | 113192 | 16169070 | Two-hybrid |
UCHL1 | NEDD8 | 110815 | 16169070 | Two-hybrid |
CUL1 | NEDD8 | 114032 | 16177058 16620772 18627766 | Affinity Capture-MS; Affinity Capture-Western |
CUL1 | NEDD8 | 110815 | 16177058 16620772 18627766 | Affinity Capture-MS; Affinity Capture-Western |
PTK2 | NEDD8 | 111719 | 16620772 | Affinity Capture-MS |
PTK2 | NEDD8 | 110815 | 16620772 | Affinity Capture-MS |
CUL4B | NEDD8 | 114028 | 16620772 | Affinity Capture-MS |
CUL4B | NEDD8 | 110815 | 16620772 | Affinity Capture-MS |
NAE1 | NEDD8 | 114402 | 16620772 | Affinity Capture-MS |
NAE1 | NEDD8 | 110815 | 16620772 | Affinity Capture-MS |
CUL3 | NEDD8 | 110815 | 16620772 17192413 | Affinity Capture-MS; Affinity Capture-Western |
CUL3 | NEDD8 | 114030 | 16620772 17192413 | Affinity Capture-MS; Affinity Capture-Western |
TP53 | NEDD8 | 110815 | 16620772 17098746 17369817 17546054 | Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex |
TP53 | NEDD8 | 113010 | 16620772 17098746 17369817 17546054 | Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex |
CUL2 | NEDD8 | 110815 | 16620772 18173839 | Affinity Capture-MS; Reconstituted Complex |
CUL2 | NEDD8 | 114031 | 16620772 18173839 | Affinity Capture-MS; Reconstituted Complex |
UBC | NEDD8 | 113164 | 16735510 | Affinity Capture-Western |
UBC | NEDD8 | 110815 | 16735510 | Affinity Capture-Western |
HGS | NEDD8 | 110815 | 16735510 | Affinity Capture-Western |
HGS | NEDD8 | 114593 | 16735510 | Affinity Capture-Western |
SIRT1 | NEDD8 | 116983 | 16998474 | Affinity Capture-Western |
SIRT1 | NEDD8 | 110815 | 16998474 | Affinity Capture-Western |
C11orf17 | NEDD8 | 110815 | 16998474 | Affinity Capture-Western |
C11orf17 | NEDD8 | 121180 | 16998474 | Affinity Capture-Western |
FBXO4 | NEDD8 | 117656 | 17353931 | Affinity Capture-MS |
FBXO4 | NEDD8 | 110815 | 17353931 | Affinity Capture-MS |
TFE3 | NEDD8 | 112888 | 17353931 | Affinity Capture-MS |
TFE3 | NEDD8 | 110815 | 17353931 | Affinity Capture-MS |
VHL | NEDD8 | 113269 | 17353931 | Affinity Capture-MS |
VHL | NEDD8 | 110815 | 17353931 | Affinity Capture-MS |
MAGED1 | NEDD8 | 114879 | 17353931 | Affinity Capture-MS |
MAGED1 | NEDD8 | 110815 | 17353931 | Affinity Capture-MS |
CUL5 | NEDD8 | 113743 | 18805092 | Co-crystal Structure |
CUL5 | NEDD8 | 110815 | 18805092 | Co-crystal Structure |
COPS6 | NEDD8 | 116176 | 19615732 | Affinity Capture-MS |
COPS6 | NEDD8 | 110815 | 19615732 | Affinity Capture-MS |
COPS5 | NEDD8 | 116183 | 19615732 | Affinity Capture-MS |
COPS5 | NEDD8 | 110815 | 19615732 | Affinity Capture-MS |
USP25 | NEDD8 | 110815 | 19615732 | Affinity Capture-MS |
USP25 | NEDD8 | 118895 | 19615732 | Affinity Capture-MS |
USP13 | NEDD8 | 114465 | 19615732 | Affinity Capture-MS |
USP13 | NEDD8 | 110815 | 19615732 | Affinity Capture-MS |
No data |
No data |
- MGI ID: MGI:97301
- Data Attributes: MGI curated and HomoloGene calculated
- ZFIN ID: ZDB-GENE-030616-588