AutismKB 2.0

Annotation Details for NEK3


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Basic Information Top
Gene Symbol:NEK3 ( HSPK36,MGC29949 )
Gene Full Name: NIMA (never in mitosis gene a)-related kinase 3
Band: 13q14.3
Quick LinksEntrez ID:4752; OMIM: 604044; Uniprot ID:NEK3_HUMAN; ENSEMBL ID: ENSG00000136098; HGNC ID: 7746
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634NAS-nucleus7522034
GO:0005737IEA-cytoplasm-
GO:0030424IEA-axon-
GO ID Evidence Qualifier GO_term References
GO:0004674NAS-protein serine/threonine kinase activity7522034
GO:0005515IPI-protein binding15618286
GO:0005524IEA-ATP binding-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0000278NAS-mitotic cell cycle7522034
GO:0006468ISS-protein phosphorylation-
GO:0030010IEA-establishment of cell polarity-
GO:0048812IEA-neuron projection morphogenesis-
GO:0051301IEA-cell division-
GO:0090043IEA-regulation of tubulin deacetylation-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1344371
  • Data Attributes: MGI curated and HomoloGene calculated
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018