AutismKB 2.0

Annotation Details for NEUROG1


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Basic Information Top
Gene Symbol:NEUROG1 ( AKA,Math4C,NEUROD3,bHLHa6,ngn1 )
Gene Full Name: neurogenin 1
Band: 5q31.1
Quick LinksEntrez ID:4762; OMIM: 601726; Uniprot ID:NGN1_HUMAN; ENSEMBL ID: ENSG00000181965; HGNC ID: 7764
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO:0043204IEA-perikaryon-
GO ID Evidence Qualifier GO_term References
GO:0000989ISS-transcription factor activity, transcription factor binding-
GO:0003677ISS-DNA binding-
GO:0003682ISS-chromatin binding-
GO:0003700TAS-transcription factor activity, sequence-specific DNA binding8816493
GO:0005515IPI-protein binding25416956
GO:0042803IDA-protein homodimerization activity20102160
GO:0070888IDA-E-box binding20102160
GO:0070888ISS-E-box binding-
GO:1990837IDA-sequence-specific double-stranded DNA binding20102160
GO ID Evidence Qualifier GO_term References
GO:0006351IEA-transcription, DNA-templated-
GO:0006357TAS-regulation of transcription from RNA polymerase II promoter8816493
GO:0007356IGI-thorax and anterior abdomen determination23419067
GO:0007399TAS-nervous system development8816493
GO:0021559IGI-trigeminal nerve development23419067
GO:0021650IGI-vestibulocochlear nerve formation23419067
GO:0030182IEA-neuron differentiation-
GO:0030432IGI-peristalsis23419067
GO:0031223IGI-auditory behavior23419067
GO:0031536IEA-positive regulation of exit from mitosis-
GO:0035112IGI-genitalia morphogenesis23419067
GO:0042472IGI-inner ear morphogenesis23419067
GO:0045165IEA-cell fate commitment-
GO:0045666ISS-positive regulation of neuron differentiation-
GO:0045944ISS-positive regulation of transcription from RNA polymerase II promoter-
GO:0048634IGI-regulation of muscle organ development23419067
GO:0048806IGI-genitalia development23419067
GO:0048839IGI-inner ear development23419067
GO:0050885IGI-neuromuscular process controlling balance23419067
GO:0051091ISS-positive regulation of sequence-specific DNA binding transcription factor activity-
GO:0060021IGI-palate development23419067
GO:0071626IGI-mastication23419067
GO:0090102IGI-cochlea development23419067
GO:0090103IGI-cochlea morphogenesis23419067
GO:0097094IGI-craniofacial suture morphogenesis23419067
GO:0098583IGI-learned vocalization behavior23419067
GO:1901078IGI-negative regulation of relaxation of muscle23419067
GO:1905747IGI-negative regulation of saliva secretion23419067
GO:1905748IGI-hard palate morphogenesis23419067
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NEUROG1RUNX1T111083520211142 Two-hybrid
NEUROG1RUNX1T110731020211142 Two-hybrid
NEUROG1CREBBP11083511239394 Affinity Capture-Western; Phenotypic Suppression; Reconstituted Complex
NEUROG1CREBBP10777711239394 Affinity Capture-Western; Phenotypic Suppression; Reconstituted Complex
NEUROG1EP30010834711239394 Phenotypic Enhancement
NEUROG1EP30011083511239394 Phenotypic Enhancement
NEUROG1SMAD111026111239394 Phenotypic Enhancement; Phenotypic Suppression; Reconstituted Complex
NEUROG1SMAD111083511239394 Phenotypic Enhancement; Phenotypic Suppression; Reconstituted Complex
TARBP2NEUROG111275820211142 Two-hybrid
TARBP2NEUROG111083520211142 Two-hybrid
CBFA2T2NEUROG111458620211142 Two-hybrid
CBFA2T2NEUROG111083520211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
NEUROG1rs2344484, rs2344485, rs8192558, rs8192559 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:107754
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-990415-174'