AutismKB 2.0

Annotation Details for NFATC1


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Basic Information Top
Gene Symbol:NFATC1 ( MGC138448,NF-ATC,NFAT2,NFATc )
Gene Full Name: nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
Band: 18q23
Quick LinksEntrez ID:4772; OMIM: 600489; Uniprot ID:NFAC1_HUMAN; ENSEMBL ID: ENSG00000131196; HGNC ID: 7775
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000790IDA-nuclear chromatin15304486
GO:0005634IDA-nucleus12370307
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005737ISS-cytoplasm-
GO:0005829TAS-cytosol-
GO:0016604IDA-nuclear body-
GO ID Evidence Qualifier GO_term References
GO:0000980ISS-RNA polymerase II distal enhancer sequence-specific DNA binding-
GO:0001085ISS-RNA polymerase II transcription factor binding-
GO:0001205ISS-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-
GO:0001225IEA-RNA polymerase II transcription coactivator binding-
GO:0003700TAS-transcription factor activity, sequence-specific DNA binding9506523
GO:0003705ISS-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-
GO:0005515IPI-protein binding17882263
GO:0005528TAS-FK506 binding8702849
GO:0048273ISS-mitogen-activated protein kinase p38 binding-
GO ID Evidence Qualifier GO_term References
GO:0006366TAS-transcription from RNA polymerase II promoter8702849
GO:0007223TAS-Wnt signaling pathway, calcium modulating pathway-
GO:0033173IDA-calcineurin-NFAT signaling cascade14979875
GO:0035556IDA-intracellular signal transduction14749367
GO:0038095TAS-Fc-epsilon receptor signaling pathway-
GO:0045893IDA-positive regulation of transcription, DNA-templated14749367
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter14979875
GO:0045944IGI-positive regulation of transcription from RNA polymerase II promoter14979875
GO:0045944ISS-positive regulation of transcription from RNA polymerase II promoter-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NFATC1PARP110665218078995 Affinity Capture-Western; Reconstituted Complex
NFATC1PARP111084518078995 Affinity Capture-Western; Reconstituted Complex
NFATC1EGR110827812560487 Reconstituted Complex
NFATC1EGR111084512560487 Reconstituted Complex
NFATC1EGR210827912560487 Reconstituted Complex
NFATC1EGR211084512560487 Reconstituted Complex
NFATC1EP30010834721413932 Biochemical Activity
NFATC1EP30011084521413932 Biochemical Activity
PIM1NFATC111131011823475 Affinity Capture-Western; Biochemical Activity
PIM1NFATC111084511823475 Affinity Capture-Western; Biochemical Activity
HDAC3NFATC111436819463978 Co-localization
HDAC3NFATC111084519463978 Co-localization
HDAC5NFATC111533121413932 Affinity Capture-Western; Biochemical Activity
HDAC5NFATC111084521413932 Affinity Capture-Western; Biochemical Activity
KAT2BNFATC111437521413932 Biochemical Activity
KAT2BNFATC111084521413932 Biochemical Activity
FOXP3NFATC111917021490927 Affinity Capture-Luminescence
FOXP3NFATC111084521490927 Affinity Capture-Luminescence
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:102469
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060503-677'