AutismKB 2.0

Annotation Details for NFATC4


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Basic Information Top
Gene Symbol:NFATC4 ( NF-ATc4,NFAT3 )
Gene Full Name: nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
Band: 14q12
Quick LinksEntrez ID:4776; OMIM: 602699; Uniprot ID:NFAC4_HUMAN; ENSEMBL ID: ENSG00000100968; HGNC ID: 7778
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus12370307
GO:0005667IEA-transcription factor complex-
GO:0005829IDA-cytosol-
GO:0016607IDA-nuclear speck-
GO ID Evidence Qualifier GO_term References
GO:0000978IEA-RNA polymerase II core promoter proximal region sequence-specific DNA binding-
GO:0001078IEA-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-
GO:0001227IGI-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding23543060
GO:0003713TAS-transcription coactivator activity7749981
GO:0005515IPI-protein binding19026640
GO:0008134IEA-transcription factor binding-
GO:0042975IEA-peroxisome proliferator activated receptor binding-
GO ID Evidence Qualifier GO_term References
GO:0001569IEA-branching involved in blood vessel morphogenesis-
GO:0006366TAS-transcription from RNA polymerase II promoter7749981
GO:0006954TAS-inflammatory response7749981
GO:0007507IEA-heart development-
GO:0008630IEA-intrinsic apoptotic signaling pathway in response to DNA damage-
GO:0030178IEA-negative regulation of Wnt signaling pathway-
GO:0032091IEA-negative regulation of protein binding-
GO:0032760IEA-positive regulation of tumor necrosis factor production-
GO:0033173IEA-calcineurin-NFAT signaling cascade-
GO:0034644IEA-cellular response to UV-
GO:0035562IEA-negative regulation of chromatin binding-
GO:0045333IEA-cellular respiration-
GO:0045944IEA-positive regulation of transcription from RNA polymerase II promoter-
GO:0048167IEA-regulation of synaptic plasticity-
GO:0050774IEA-negative regulation of dendrite morphogenesis-
GO:0051145IEA-smooth muscle cell differentiation-
GO:0055001IEA-muscle cell development-
GO:0071285IEA-cellular response to lithium ion-
GO:1902894IGI-negative regulation of pri-miRNA transcription from RNA polymerase II promoter23543060
GO:1904637IEA-cellular response to ionomycin-
GO:2000297IEA-negative regulation of synapse maturation-
GO:2001235IEA-positive regulation of apoptotic signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NFATC4CREBBP10777711514544 Affinity Capture-Western; Reconstituted Complex
NFATC4CREBBP11084911514544 Affinity Capture-Western; Reconstituted Complex
YWHAZNFATC411336610611249 Reconstituted Complex
YWHAZNFATC411084910611249 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1920431
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070912-659'