AutismKB 2.0

Annotation Details for ATP1A3


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Basic Information Top
Gene Symbol:ATP1A3 ( DYT12,MGC13276,RDP )
Gene Full Name: ATPase, Na+/K+ transporting, alpha 3 polypeptide
Band: 19q13.2
Quick LinksEntrez ID:478; OMIM: 182350; Uniprot ID:AT1A3_HUMAN; ENSEMBL ID: ENSG00000105409; HGNC ID: 801
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO:0005783IDA-endoplasmic reticulum15260953
GO:0005794IDA-Golgi apparatus15260953
GO:0005886IDA-plasma membrane15260953
GO:0005886TAS-plasma membrane-
GO:0005890IC-sodium:potassium-exchanging ATPase complex15260953
GO:0005890IDA-sodium:potassium-exchanging ATPase complex10636900
GO:0005890NAS-sodium:potassium-exchanging ATPase complex26224839
GO:0016020ISS-membrane-
GO:0016021NAS-integral component of membrane15260953
GO:0030424IDA-axon26224839
GO:0032809IC-neuronal cell body membrane26224839
GO:0042383IEA-sarcolemma-
GO:0043025IDA-neuronal cell body26224839
GO:0043209IEA-myelin sheath-
GO:0044326IEA-dendritic spine neck-
GO:0044327IEA-dendritic spine head-
GO:0045202ISS-synapse-
GO:1903561IDA-extracellular vesicle24769233
GO ID Evidence Qualifier GO_term References
GO:0001540IEA-amyloid-beta binding-
GO:0005391IDA-sodium:potassium-exchanging ATPase activity10636900
GO:0005391IMP-sodium:potassium-exchanging ATPase activity15260953
GO:0005391NAS-sodium:potassium-exchanging ATPase activity26224839
GO:0005524NAS-ATP binding15260953
GO:0031748IEA-D1 dopamine receptor binding-
GO:0043395IEA-heparan sulfate proteoglycan binding-
GO:0046872IEA-metal ion binding-
GO:0051087IPI-chaperone binding10636900
GO:0086037IEA-sodium:potassium-exchanging ATPase activity involved in regulation of cardiac muscle cell membrane potential-
GO:1990239NAS-steroid hormone binding11546672
GO ID Evidence Qualifier GO_term References
GO:0006883IDA-cellular sodium ion homeostasis10636900
GO:0007613IEA-memory-
GO:0008344IEA-adult locomotory behavior-
GO:0008542IEA-visual learning-
GO:0010107IDA-potassium ion import10636900
GO:0010248IEA-establishment or maintenance of transmembrane electrochemical gradient-
GO:0021987IEA-cerebral cortex development-
GO:0030007IDA-cellular potassium ion homeostasis10636900
GO:0034220TAS-ion transmembrane transport-
GO:0035235IEA-ionotropic glutamate receptor signaling pathway-
GO:0036376IDA-sodium ion export from cell10636900
GO:0042493IEA-response to drug-
GO:0060048IEA-cardiac muscle contraction-
GO:0060075TAS-regulation of resting membrane potential26224839
GO:0071300IEA-cellular response to retinoic acid-
GO:0071383NAS-cellular response to steroid hormone stimulus11546672
GO:0086036IEA-regulation of cardiac muscle cell membrane potential-
GO:0086064TAS-cell communication by electrical coupling involved in cardiac conduction19683723
GO:0097067IEA-cellular response to thyroid hormone stimulus-
GO:1903416NAS-response to glycoside11546672
GO:1903779TAS-regulation of cardiac conduction-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:88107
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-001212-7'