AutismKB 2.0

Annotation Details for NFX1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NFX1 ( DKFZp779G2416,MGC20369,NFX2 )
Gene Full Name: nuclear transcription factor, X-box binding 1
Band: 9p12
Quick LinksEntrez ID:4799; OMIM: 603255; Uniprot ID:NFX1_HUMAN; ENSEMBL ID: ENSG00000086102; HGNC ID: 7803
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IBA-nucleus-
GO:0005634IDA-nucleus-
GO:0005730IDA-nucleolus-
GO:0005829IDA-cytosol-
GO:0005886IDA-plasma membrane-
GO ID Evidence Qualifier GO_term References
GO:0000977IDA-RNA polymerase II regulatory region sequence-specific DNA binding7964459
GO:0001078IDA-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding7964459
GO:0003700TAS-transcription factor activity, sequence-specific DNA binding7964459
GO:0003723IDA-RNA binding22658674
GO:0008270IEA-zinc ion binding-
GO:0016874IEA-ligase activity-
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter7964459
GO:0006366TAS-transcription from RNA polymerase II promoter7964459
GO:0006954TAS-inflammatory response7964459
GO:0016032IEA-viral process-
GO:0045347IEA-negative regulation of MHC class II biosynthetic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NUP62NFX111716511073998 Reconstituted Complex
NUP62NFX111086511073998 Reconstituted Complex
NUP98NFX111098211073998 Reconstituted Complex
NUP98NFX111086511073998 Reconstituted Complex
NUP214NFX111086511073998 Reconstituted Complex
NUP214NFX111371711073998 Reconstituted Complex
NUP153NFX111086511073998 Reconstituted Complex
NUP153NFX111529711073998 Reconstituted Complex
SIN3ANFX111086518505829 Affinity Capture-Western; Reconstituted Complex
SIN3ANFX111743918505829 Affinity Capture-Western; Reconstituted Complex
UBE2NNFX111086519690564 Two-hybrid
UBE2NNFX111318219690564 Two-hybrid
MAML3NFX111086520211142 Two-hybrid
MAML3NFX112070420211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1921414
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved