AutismKB 2.0

Annotation Details for NFYA


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Basic Information Top
Gene Symbol:NFYA ( CBF-A,CBF-B,FLJ11236,HAP2,NF-YA )
Gene Full Name: nuclear transcription factor Y, alpha
Band: 6p21.1
Quick LinksEntrez ID:4800; OMIM: 189903; Uniprot ID:NFYA_HUMAN; ENSEMBL ID: ENSG00000001167; HGNC ID: 7804
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus15243141
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0016602IDA-CCAAT-binding factor complex15243141
GO:0032993IDA-protein-DNA complex11256944
GO ID Evidence Qualifier GO_term References
GO:0001046ISS-core promoter sequence-specific DNA binding-
GO:0003677IDA-DNA binding15243141
GO:0003700IEA-transcription factor activity, sequence-specific DNA binding-
GO:0005515IPI-protein binding10571058
GO:0044212IDAcontributes_totranscription regulatory region DNA binding11256944
GO ID Evidence Qualifier GO_term References
GO:0006355IDA-regulation of transcription, DNA-templated15243141
GO:0006366TAS-transcription from RNA polymerase II promoter2000400
GO:0045540TAS-regulation of cholesterol biosynthetic process-
GO:0045893ISS-positive regulation of transcription, DNA-templated-
GO:0048511IEA-rhythmic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NFYABRCA110714011777930 Affinity Capture-Western
NFYABRCA111086611777930 Affinity Capture-Western
NFYAATF6B11086611158310 Two-hybrid
NFYAATF6B10777811158310 Two-hybrid
NFYAELF11108669668064 Reconstituted Complex
NFYAELF11083129668064 Reconstituted Complex
NFYAHMGA11108669388234 Far Western
NFYAHMGA11094029388234 Far Western
NFYAJUN11086611903046 Affinity Capture-Western
NFYAJUN10992811903046 Affinity Capture-Western
NFYBNFYA1108668051128 15831478 17098936 Affinity Capture-Western; Reconstituted Complex
NFYBNFYA1108678051128 15831478 17098936 Affinity Capture-Western; Reconstituted Complex
SPI1NFYA1108669668064 Reconstituted Complex
SPI1NFYA1125669668064 Reconstituted Complex
ZHX1NFYA11086610441475 10571058 Reconstituted Complex; Two-hybrid
ZHX1NFYA11640610441475 10571058 Reconstituted Complex; Two-hybrid
SRFNFYA11086610571058 Reconstituted Complex; Two-hybrid
SRFNFYA11260010571058 Reconstituted Complex; Two-hybrid
ATF6NFYA11658611158310 Two-hybrid
ATF6NFYA11086611158310 Two-hybrid
TAF6NFYA11274111689552 Reconstituted Complex
TAF6NFYA11086611689552 Reconstituted Complex
TAF11NFYA11086611689552 Reconstituted Complex
TAF11NFYA11274511689552 Reconstituted Complex
TAF12NFYA11086611689552 Reconstituted Complex
TAF12NFYA11274611689552 Reconstituted Complex
TP53NFYA11086615831478 Affinity Capture-Western; Reconstituted Complex
TP53NFYA11301015831478 Affinity Capture-Western; Reconstituted Complex
APPBP2NFYA11576916189514 Two-hybrid
APPBP2NFYA11086616189514 Two-hybrid
PWP1NFYA11086620211142 Two-hybrid
PWP1NFYA11631020211142 Two-hybrid
PAPOLGNFYA12233820211142 Two-hybrid
PAPOLGNFYA11086620211142 Two-hybrid
NFYCNFYA11086820936779 Two-hybrid
NFYCNFYA11086620936779 Two-hybrid
SREBF2NFYA11259920936779 Two-hybrid
SREBF2NFYA11086620936779 Two-hybrid
Gene Symbol Interactant Interaction ID References Description
SRFNFYA19681110571058 NF-YA interacts with SRF. This interaction was modeled on a demonstrated interaction between NF-YA from an unspecified species and SRF from human.
ZHX1NFYA19681010571058 NF-YA interacts with ZHX1. This interaction was modeled on a demonstrated interaction between NF-YA from an unspecified species and ZHX1 from human.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:97316
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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