AutismKB 2.0

Annotation Details for ATP1B1


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Basic Information Top
Gene Symbol:ATP1B1 ( ATP1B,MGC1798 )
Gene Full Name: ATPase, Na+/K+ transporting, beta 1 polypeptide
Band: 1q24.2
Quick LinksEntrez ID:481; OMIM: 182330; Uniprot ID:AT1B1_HUMAN; ENSEMBL ID: ENSG00000143153; HGNC ID: 804
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622IEA-intracellular-
GO:0005886IDA-plasma membrane18522992
GO:0005886TAS-plasma membrane-
GO:0005890IDA-sodium:potassium-exchanging ATPase complex10636900
GO:0005890ISS-sodium:potassium-exchanging ATPase complex-
GO:0005901IEA-caveola-
GO:0014704ISS-intercalated disc-
GO:0016020IDA-membrane23954377
GO:0016323IEA-basolateral plasma membrane-
GO:0016324IEA-apical plasma membrane-
GO:0042383ISS-sarcolemma-
GO:0043209IEA-myelin sheath-
GO:0070062IDA-extracellular exosome20458337
GO:1903561IDA-extracellular vesicle24769233
GO ID Evidence Qualifier GO_term References
GO:0001671IDA-ATPase activator activity10636900
GO:0005391IDAcontributes_tosodium:potassium-exchanging ATPase activity10636900
GO:0005391ISScontributes_tosodium:potassium-exchanging ATPase activity-
GO:0005515IPI-protein binding17947299
GO:0005524IDAcontributes_toATP binding23954377
GO:0008022IEA-protein C-terminus binding-
GO:0008144IPIcontributes_todrug binding23954377
GO:0016887IDAcontributes_toATPase activity23954377
GO:0019901IEA-protein kinase binding-
GO:0023026IDA-MHC class II protein complex binding20458337
GO:0030955IDAcontributes_topotassium ion binding23954377
GO:0031402IDAcontributes_tosodium ion binding23954377
GO:0051117IPI-ATPase binding10636900
GO ID Evidence Qualifier GO_term References
GO:0001666IEA-response to hypoxia-
GO:0006874ISS-cellular calcium ion homeostasis-
GO:0006883IDA-cellular sodium ion homeostasis10636900
GO:0007155IEA-cell adhesion-
GO:0010107IDA-potassium ion import10636900
GO:0010248IEA-establishment or maintenance of transmembrane electrochemical gradient-
GO:0010468ISS-regulation of gene expression-
GO:0010882ISS-regulation of cardiac muscle contraction by calcium ion signaling-
GO:0030007IDA-cellular potassium ion homeostasis10636900
GO:0032781IDA-positive regulation of ATPase activity10636900
GO:0034220TAS-ion transmembrane transport-
GO:0036376IDA-sodium ion export from cell10636900
GO:0036376ISS-sodium ion export from cell-
GO:0044861TAS-protein transport into plasma membrane raft19683723
GO:0046034IDA-ATP metabolic process23954377
GO:0050821IDA-protein stabilization10636900
GO:0050821ISS-protein stabilization-
GO:0050900TAS-leukocyte migration-
GO:0055119ISS-relaxation of cardiac muscle-
GO:0060048ISS-cardiac muscle contraction-
GO:0072659IDA-protein localization to plasma membrane18522992
GO:0086009IDA-membrane repolarization19542013
GO:0086013IC-membrane repolarization during cardiac muscle cell action potential19542013
GO:0086064TAS-cell communication by electrical coupling involved in cardiac conduction19683723
GO:1901018IDA-positive regulation of potassium ion transmembrane transporter activity10636900
GO:1903278IDA-positive regulation of sodium ion export from cell10636900
GO:1903281ISS-positive regulation of calcium:sodium antiporter activity-
GO:1903288IDA-positive regulation of potassium ion import10636900
GO:1903779TAS-regulation of cardiac conduction-
GO:1990573ISS-potassium ion import across plasma membrane-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FXYD1ATP1B111136314597563 Affinity Capture-Western
FXYD1ATP1B110697114597563 Affinity Capture-Western
C1orf103ATP1B112090516169070 Two-hybrid
C1orf103ATP1B110697116169070 Two-hybrid
UBCATP1B111316418522992 Affinity Capture-Western
UBCATP1B110697118522992 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:88108
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-001127-3'