AutismKB 2.0

Annotation Details for CNOT3


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Basic Information Top
Gene Symbol:CNOT3 ( KIAA0691,LENG2,NOT3,NOT3H )
Gene Full Name: CCR4-NOT transcription complex, subunit 3
Band: 19q13.42
Quick LinksEntrez ID:4849; OMIM: 604910; Uniprot ID:CNOT3_HUMAN; ENSEMBL ID: ENSG00000088038; HGNC ID: 7879
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000932IBA-P-body-
GO:0000932ISS-P-body-
GO:0005634IEA-nucleus-
GO:0005829TAS-cytosol-
GO:0030014IDA-CCR4-NOT complex19558367
GO:0030015IBA-CCR4-NOT core complex-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding10637334
GO ID Evidence Qualifier GO_term References
GO:0000288IBA-nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-
GO:0000289TAS-nuclear-transcribed mRNA poly(A) tail shortening-
GO:0001829IEA-trophectodermal cell differentiation-
GO:0006351IEA-transcription, DNA-templated-
GO:0006355IEA-regulation of transcription, DNA-templated-
GO:0006977TAS-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-
GO:0017148IBA-negative regulation of translation-
GO:0031047IEA-gene silencing by RNA-
GO:2000036IMP-regulation of stem cell population maintenance22367759
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CNOT3CNOT211091016189514 Two-hybrid
CNOT3CNOT211091116189514 Two-hybrid
CNOT8CNOT311474410637334 Affinity Capture-Western; Two-hybrid
CNOT8CNOT311091110637334 Affinity Capture-Western; Two-hybrid
CAND2CNOT311670112207886 Reconstituted Complex; Two-hybrid
CAND2CNOT311091112207886 Reconstituted Complex; Two-hybrid
SRRM1CNOT311091116159877 Affinity Capture-MS
SRRM1CNOT311554416159877 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2385261
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-5838'