Annotation Details for CNOT4

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Basic Information Top

Gene Symbol:	CNOT4 ( CLONE243,NOT4,NOT4H )
Gene Full Name:	CCR4-NOT transcription complex, subunit 4
Band:	7q33
Quick Links	Entrez ID:4850; OMIM: 604911; Uniprot ID:CNOT4_HUMAN; ENSEMBL ID: ENSG00000080802; HGNC ID: 7880
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

AlzGene, PDGene and SZGene

Gene Ontology

Cellular Component:3 results
Molecular Function:4 results
Biological Process:3 results

GO ID	Evidence	Qualifier	GO_term	References
GO:0005634	IEA	-	nucleus	-
GO:0005829	TAS	-	cytosol	-
GO:0030014	IDA	colocalizes_with	CCR4-NOT complex	19558367

GO ID	Evidence	Qualifier	GO_term	References
GO:0003723	IDA	-	RNA binding	22681889
GO:0004842	IDA	-	ubiquitin-protein transferase activity	15001359
GO:0005515	IPI	-	protein binding	15001359
GO:0046872	IEA	-	metal ion binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0000289	TAS	-	nuclear-transcribed mRNA poly(A) tail shortening	-
GO:0006977	TAS	-	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	-
GO:0051865	IDA	-	protein autoubiquitination	15001359

Protein-Protein Interaction

BioGRID:14 results
BIND:0 results
HPRD:0 results

Gene Symbol	Interactant	Interaction ID	References	Description
CNOT1	CNOT4	116660	10637334	Two-hybrid
CNOT1	CNOT4	110912	10637334	Two-hybrid
UBE2E3	CNOT4	115740	19690564	Two-hybrid
UBE2E3	CNOT4	110912	19690564	Two-hybrid
UBE2D4	CNOT4	110912	19690564	Two-hybrid
UBE2D4	CNOT4	119641	19690564	Two-hybrid
UBE2W	CNOT4	110912	19690564	Two-hybrid
UBE2W	CNOT4	120572	19690564	Two-hybrid
UBE2D2	CNOT4	110912	19690564	Two-hybrid
UBE2D2	CNOT4	113170	19690564	Two-hybrid
UBE2D3	CNOT4	110912	19690564	Two-hybrid
UBE2D3	CNOT4	113171	19690564	Two-hybrid
UBE2N	CNOT4	113182	19690564	Two-hybrid
UBE2N	CNOT4	110912	19690564	Two-hybrid

AlzGene, PDGene and SZGene

Animal Model

Mouse:1 results
Fruit Fly:0 results

MGI ID: MGI:1859026
Data Attributes: MGI curated