AutismKB 2.0

Annotation Details for NOV


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Basic Information Top
Gene Symbol:NOV ( CCN3,IGFBP9 )
Gene Full Name: nephroblastoma overexpressed gene
Band: 8q24.12
Quick LinksEntrez ID:4856; OMIM: 164958; Uniprot ID:NOV_HUMAN; ENSEMBL ID: ENSG00000136999; HGNC ID: 7885
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576ISS-extracellular region-
GO:0005615IEA-extracellular space-
GO:0005737IMP-cytoplasm15181016
GO:0005737ISS-cytoplasm-
GO:0005921IMP-gap junction15181016
GO:0005921ISS-gap junction-
GO:0030424IEA-axon-
GO:0030425IEA-dendrite-
GO:0031012IEA-extracellular matrix-
GO:0043025IEA-neuronal cell body-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO ID Evidence Qualifier GO_term References
GO:0005112IPI-Notch binding12050162
GO:0005178IPI-integrin binding12695522
GO:0005515IPI-protein binding9927660
GO:0005520IEA-insulin-like growth factor binding-
GO:0008083IEA-growth factor activity-
GO ID Evidence Qualifier GO_term References
GO:0001525IDA-angiogenesis12695522
GO:0002062IMP-chondrocyte differentiation21871891
GO:0010468IEA-regulation of gene expression-
GO:0010761IDA-fibroblast migration15611078
GO:0010832IDA-negative regulation of myotube differentiation12050162
GO:0014909IDA-smooth muscle cell migration20139355
GO:0030308IMP-negative regulation of cell growth15181016
GO:0033627IDA-cell adhesion mediated by integrin12695522
GO:0035767IDA-endothelial cell chemotaxis12695522
GO:0042347IMP-negative regulation of NF-kappaB import into nucleus21063504
GO:0044342ISS-type B pancreatic cell proliferation-
GO:0045747IDA-positive regulation of Notch signaling pathway12050162
GO:0046676ISS-negative regulation of insulin secretion-
GO:0048659IDA-smooth muscle cell proliferation20139355
GO:0050728ISS-negative regulation of inflammatory response-
GO:0060326IDA-cell chemotaxis15611078
GO:0060392ISS-negative regulation of SMAD protein import into nucleus-
GO:0061484IMP-hematopoietic stem cell homeostasis17463287
GO:0071603IDA-endothelial cell-cell adhesion12695522
GO:0090027IMP-negative regulation of monocyte chemotaxis21063504
GO:1902731IMP-negative regulation of chondrocyte proliferation21871891
GO:1904057ISS-negative regulation of sensory perception of pain-
GO:1990523ISS-bone regeneration-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NOVCDK211091815647383 Affinity Capture-Western
NOVCDK210745215647383 Affinity Capture-Western
NOVFBLN11109189927660 Reconstituted Complex; Two-hybrid
NOVFBLN11084869927660 Reconstituted Complex; Two-hybrid
NOVFN111091812902636 Reconstituted Complex
NOVFN110862112902636 Reconstituted Complex
NOVIGF111091810084601 Reconstituted Complex
NOVIGF110970010084601 Reconstituted Complex
NOVIGF211091810084601 Reconstituted Complex
NOVIGF210970210084601 Reconstituted Complex
NOVINS11091810084601 Reconstituted Complex
NOVINS10984210084601 Reconstituted Complex
NOVITGAV11091812902636 Reconstituted Complex
NOVITGAV10989112902636 Reconstituted Complex
NOVNOTCH111091312050162 Affinity Capture-Western; Reconstituted Complex
NOVNOTCH111091812050162 Affinity Capture-Western; Reconstituted Complex
POLR2LNOV11091810474687 Two-hybrid
POLR2LNOV11143710474687 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:109185
  • Data Attributes: MGI curated and HomoloGene calculated
No data