AutismKB 2.0

Annotation Details for NPAS2


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Basic Information Top
Gene Symbol:NPAS2 ( FLJ23138,MGC71151,MOP4,PASD4,bHLHe9 )
Gene Full Name: neuronal PAS domain protein 2
Band: 2q11.2
Quick LinksEntrez ID:4862; OMIM: 603347; Uniprot ID:NPAS2_HUMAN; ENSEMBL ID: ENSG00000170485; HGNC ID: 7895
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus14645221
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005667IPI-transcription factor complex9576906
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0001047ISS-core promoter binding-
GO:0003677IDA-DNA binding11441146
GO:0003677IPI-DNA binding9576906
GO:0003700IEA-transcription factor activity, sequence-specific DNA binding-
GO:0005515IPI-protein binding14645221
GO:0046872IEA-metal ion binding-
GO:0046983IEA-protein dimerization activity-
GO:0051879IDA-Hsp90 protein binding9079689
GO ID Evidence Qualifier GO_term References
GO:0006351IEA-transcription, DNA-templated-
GO:0006974IEA-cellular response to DNA damage stimulus-
GO:0007417TAS-central nervous system development9012850
GO:0007623TAS-circadian rhythm-
GO:0019216TAS-regulation of lipid metabolic process-
GO:0032922ISS-circadian regulation of gene expression-
GO:0045739IMP-positive regulation of DNA repair18819933
GO:0045893IDA-positive regulation of transcription, DNA-templated11441146
GO:0045893IMP-positive regulation of transcription, DNA-templated18819933
GO:0045944IGI-positive regulation of transcription from RNA polymerase II promoter9576906
GO:0051775IDA-response to redox state11441146
GO:0060548IMP-negative regulation of cell death18819933
GO:2001020IMP-regulation of response to DNA damage stimulus18819933
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NPAS2ARNTL1109239576906 11439184 Reconstituted Complex; Two-hybrid
NPAS2ARNTL1068999576906 11439184 Reconstituted Complex; Two-hybrid
NPAS2CREBBP11092314645221 Reconstituted Complex
NPAS2CREBBP10777714645221 Reconstituted Complex
NPAS2EP30010834714645221 Reconstituted Complex
NPAS2EP30011092314645221 Reconstituted Complex
NPAS2HSP90AA11109239079689 Reconstituted Complex
NPAS2HSP90AA11095529079689 Reconstituted Complex
RARANPAS211092311439184 Reconstituted Complex; Two-hybrid
RARANPAS211184911439184 Reconstituted Complex; Two-hybrid
RXRANPAS211092311439184 Reconstituted Complex; Two-hybrid
RXRANPAS211216811439184 Reconstituted Complex; Two-hybrid
NCOA3NPAS211092314645221 Reconstituted Complex
NCOA3NPAS211384114645221 Reconstituted Complex
KAT2BNPAS211092314645221 Reconstituted Complex
KAT2BNPAS211437514645221 Reconstituted Complex
RHOXF1NPAS211092320211142 Two-hybrid
RHOXF1NPAS212770820211142 Two-hybrid
ZSCAN1NPAS211092320211142 Two-hybrid
ZSCAN1NPAS212982520211142 Two-hybrid
HESX1NPAS211092320211142 Two-hybrid
HESX1NPAS211434720211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
NPAS2NPAS2_57SNPs, rs11123857, rs13025524, rs6543004 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:109232
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030408-3'