Annotation Details for ATP2A1
Basic Information Top
Gene Symbol: | ATP2A1 ( ATP2A,SERCA1 ) |
---|---|
Gene Full Name: | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
Band: | 16p11.2 |
Quick Links | Entrez ID:487; OMIM: 108730; Uniprot ID:AT2A1_HUMAN; ENSEMBL ID: ENSG00000196296; HGNC ID: 811 |
Relate to Another Database: | SFARIGene; denovo-db |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0005739 | IEA | - | mitochondrion | - |
GO:0005789 | TAS | - | endoplasmic reticulum membrane | - |
GO:0016021 | NAS | - | integral component of membrane | 9405806 |
GO:0016529 | NAS | - | sarcoplasmic reticulum | 8841193 |
GO:0031095 | TAS | - | platelet dense tubular network membrane | - |
GO:0033017 | IC | - | sarcoplasmic reticulum membrane | 8040329 |
GO:0033017 | ISS | - | sarcoplasmic reticulum membrane | - |
GO:0033017 | TAS | - | sarcoplasmic reticulum membrane | 11402072 |
GO:0034704 | IC | - | calcium channel complex | 11402072 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0005388 | IDA | - | calcium-transporting ATPase activity | 8729696 |
GO:0005388 | TAS | - | calcium-transporting ATPase activity | - |
GO:0005509 | IMP | - | calcium ion binding | 9405806 |
GO:0005515 | IPI | - | protein binding | 9295312 |
GO:0005524 | IEA | - | ATP binding | - |
GO:0042803 | IPI | - | protein homodimerization activity | 11402072 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0006816 | IMP | - | calcium ion transport | 9405806 |
GO:0008637 | IMP | - | apoptotic mitochondrial changes | 19061639 |
GO:0031448 | IDA | - | positive regulation of fast-twitch skeletal muscle fiber contraction | 12479237 |
GO:0032470 | IMP | - | positive regulation of endoplasmic reticulum calcium ion concentration | 11402072 |
GO:0032471 | IMP | - | negative regulation of endoplasmic reticulum calcium ion concentration | 11402072 |
GO:0034220 | TAS | - | ion transmembrane transport | - |
GO:0034976 | IMP | - | response to endoplasmic reticulum stress | 19061639 |
GO:0051561 | IMP | - | positive regulation of mitochondrial calcium ion concentration | 19061639 |
GO:0051659 | IMP | - | maintenance of mitochondrion location | 19061639 |
GO:0070059 | IMP | - | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | 19061639 |
GO:0070509 | IMP | - | calcium ion import | 8040329 |
GO:0070588 | IEA | - | calcium ion transmembrane transport | - |
GO:0090076 | IDA | - | relaxation of skeletal muscle | 8841193 |
GO:0099132 | IEA | - | ATP hydrolysis coupled cation transmembrane transport | - |
GO:1903779 | TAS | - | regulation of cardiac conduction | - |
Gene Symbol | Interactant | Interaction ID | References | Description |
---|---|---|---|---|
PLN | ATP2A1 | 111365 | 10551848 11526231 12032137 | Affinity Capture-Western |
PLN | ATP2A1 | 106977 | 10551848 11526231 12032137 | Affinity Capture-Western |
SLN | ATP2A1 | 112474 | 12032137 12692302 | Affinity Capture-Western |
SLN | ATP2A1 | 106977 | 12032137 12692302 | Affinity Capture-Western |
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No data |
- MGI ID: MGI:105058
- Data Attributes: MGI curated and HomoloGene calculated
- ZFIN ID: ZDB-GENE-020905-1