AutismKB 2.0

Annotation Details for ATP2A1


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Basic Information Top
Gene Symbol:ATP2A1 ( ATP2A,SERCA1 )
Gene Full Name: ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Band: 16p11.2
Quick LinksEntrez ID:487; OMIM: 108730; Uniprot ID:AT2A1_HUMAN; ENSEMBL ID: ENSG00000196296; HGNC ID: 811
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005739IEA-mitochondrion-
GO:0005789TAS-endoplasmic reticulum membrane-
GO:0016021NAS-integral component of membrane9405806
GO:0016529NAS-sarcoplasmic reticulum8841193
GO:0031095TAS-platelet dense tubular network membrane-
GO:0033017IC-sarcoplasmic reticulum membrane8040329
GO:0033017ISS-sarcoplasmic reticulum membrane-
GO:0033017TAS-sarcoplasmic reticulum membrane11402072
GO:0034704IC-calcium channel complex11402072
GO ID Evidence Qualifier GO_term References
GO:0005388IDA-calcium-transporting ATPase activity8729696
GO:0005388TAS-calcium-transporting ATPase activity-
GO:0005509IMP-calcium ion binding9405806
GO:0005515IPI-protein binding9295312
GO:0005524IEA-ATP binding-
GO:0042803IPI-protein homodimerization activity11402072
GO ID Evidence Qualifier GO_term References
GO:0006816IMP-calcium ion transport9405806
GO:0008637IMP-apoptotic mitochondrial changes19061639
GO:0031448IDA-positive regulation of fast-twitch skeletal muscle fiber contraction12479237
GO:0032470IMP-positive regulation of endoplasmic reticulum calcium ion concentration11402072
GO:0032471IMP-negative regulation of endoplasmic reticulum calcium ion concentration11402072
GO:0034220TAS-ion transmembrane transport-
GO:0034976IMP-response to endoplasmic reticulum stress19061639
GO:0051561IMP-positive regulation of mitochondrial calcium ion concentration19061639
GO:0051659IMP-maintenance of mitochondrion location19061639
GO:0070059IMP-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress19061639
GO:0070509IMP-calcium ion import8040329
GO:0070588IEA-calcium ion transmembrane transport-
GO:0090076IDA-relaxation of skeletal muscle8841193
GO:0099132IEA-ATP hydrolysis coupled cation transmembrane transport-
GO:1903779TAS-regulation of cardiac conduction-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PLNATP2A111136510551848 11526231 12032137 Affinity Capture-Western
PLNATP2A110697710551848 11526231 12032137 Affinity Capture-Western
SLNATP2A111247412032137 12692302 Affinity Capture-Western
SLNATP2A110697712032137 12692302 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:105058
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-020905-1'