Annotation Details for ATP2A2


Gene Symbol: | ATP2A2 ( ATP2B,DAR,DD,DKFZp686P0211,FLJ20293,FLJ38063,MGC45367,SERCA2 ) |
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Gene Full Name: | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
Band: | 12q24.11 |
Quick Links | Entrez ID:488; OMIM: 108740; Uniprot ID:AT2A2_HUMAN; ENSEMBL ID: ENSG00000174437; HGNC ID: 812 |
Relate to Another Database: | SFARIGene; denovo-db |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0005654 | IDA | - | nucleoplasm | - |
GO:0005783 | IDA | - | endoplasmic reticulum | 16081076 |
GO:0005789 | IDA | - | endoplasmic reticulum membrane | 11402072 |
GO:0005789 | TAS | - | endoplasmic reticulum membrane | - |
GO:0005887 | TAS | - | integral component of plasma membrane | 2844796 |
GO:0012506 | IEA | - | vesicle membrane | - |
GO:0016020 | IDA | - | membrane | 22375059 |
GO:0016529 | IDA | - | sarcoplasmic reticulum | 12804600 |
GO:0031095 | TAS | - | platelet dense tubular network membrane | - |
GO:0031234 | IEA | - | extrinsic component of cytoplasmic side of plasma membrane | - |
GO:0033017 | TAS | - | sarcoplasmic reticulum membrane | 19095005 |
GO:0043234 | IEA | - | protein complex | - |
GO:0048471 | IEA | - | perinuclear region of cytoplasm | - |
GO:0097470 | IEA | - | ribbon synapse | - |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0005388 | IDA | - | calcium-transporting ATPase activity | 16402920 |
GO:0005388 | TAS | - | calcium-transporting ATPase activity | - |
GO:0005509 | IDA | - | calcium ion binding | 16402920 |
GO:0005515 | IPI | - | protein binding | 17526652 |
GO:0005524 | IEA | - | ATP binding | - |
GO:0019899 | IPI | - | enzyme binding | 21903937 |
GO:0031775 | IEA | - | lutropin-choriogonadotropic hormone receptor binding | - |
GO:0044548 | IPI | - | S100 protein binding | 12804600 |
GO:0086039 | IC | - | calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential | 16402920 |
GO:0086039 | ISS | - | calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential | - |
GO:0086039 | TAS | - | calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential | 22679139 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0002026 | IEA | - | regulation of the force of heart contraction | - |
GO:0006984 | IEA | - | ER-nucleus signaling pathway | - |
GO:0006996 | IEA | - | organelle organization | - |
GO:0007155 | TAS | - | cell adhesion | 10080178 |
GO:0008544 | TAS | - | epidermis development | 10080178 |
GO:0010460 | TAS | - | positive regulation of heart rate | 22679139 |
GO:0010882 | IEA | - | regulation of cardiac muscle contraction by calcium ion signaling | - |
GO:0014883 | IEA | - | transition between fast and slow fiber | - |
GO:0014898 | IEA | - | cardiac muscle hypertrophy in response to stress | - |
GO:0032469 | IDA | - | endoplasmic reticulum calcium ion homeostasis | 16402920 |
GO:0032470 | IDA | - | positive regulation of endoplasmic reticulum calcium ion concentration | 16402920 |
GO:0033292 | IEA | - | T-tubule organization | - |
GO:0034220 | TAS | - | ion transmembrane transport | - |
GO:0034599 | IEA | - | cellular response to oxidative stress | - |
GO:0034976 | ISS | - | response to endoplasmic reticulum stress | - |
GO:0045822 | IEA | - | negative regulation of heart contraction | - |
GO:0055119 | IEA | - | relaxation of cardiac muscle | - |
GO:0070296 | TAS | - | sarcoplasmic reticulum calcium ion transport | 19095005 |
GO:0070588 | IDA | - | calcium ion transmembrane transport | 16402920 |
GO:0086036 | IC | - | regulation of cardiac muscle cell membrane potential | 16402920 |
GO:0086036 | ISS | - | regulation of cardiac muscle cell membrane potential | - |
GO:0086036 | TAS | - | regulation of cardiac muscle cell membrane potential | 22679139 |
GO:0098909 | ISS | - | regulation of cardiac muscle cell action potential involved in regulation of contraction | - |
GO:0099132 | IEA | - | ATP hydrolysis coupled cation transmembrane transport | - |
GO:1903233 | IEA | - | regulation of calcium ion-dependent exocytosis of neurotransmitter | - |
GO:1903515 | IDA | - | calcium ion transport from cytosol to endoplasmic reticulum | 16402920 |
GO:1903779 | TAS | - | regulation of cardiac conduction | - |
GO:1990036 | IC | - | calcium ion import into sarcoplasmic reticulum | 16402920 |
GO:1990036 | ISS | - | calcium ion import into sarcoplasmic reticulum | - |
Gene Symbol | Interactant | Interaction ID | References | Description |
---|---|---|---|---|
PLN | ATP2A2 | 111365 | 10809745 11854448 12032137 | Affinity Capture-Western; Reconstituted Complex |
PLN | ATP2A2 | 106978 | 10809745 11854448 12032137 | Affinity Capture-Western; Reconstituted Complex |
SLN | ATP2A2 | 112474 | 12032137 | Affinity Capture-Western |
SLN | ATP2A2 | 106978 | 12032137 | Affinity Capture-Western |
S100A1 | ATP2A2 | 112179 | 12804600 | Affinity Capture-Western |
S100A1 | ATP2A2 | 106978 | 12804600 | Affinity Capture-Western |
PTP4A3 | ATP2A2 | 116327 | 17353931 | Affinity Capture-MS |
PTP4A3 | ATP2A2 | 106978 | 17353931 | Affinity Capture-MS |
HGS | ATP2A2 | 114593 | 19019082 | Reconstituted Complex |
HGS | ATP2A2 | 106978 | 19019082 | Reconstituted Complex |
No data |
No data |
- MGI ID: MGI:88110
- Data Attributes: MGI curated and HomoloGene calculated
- ZFIN ID: ZDB-GENE-030131-867