AutismKB 2.0

Annotation Details for ACR


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Basic Information Top
Gene Symbol:ACR ( - )
Gene Full Name: acrosin
Band: 22q13.33
Quick LinksEntrez ID:49; OMIM: 102480; Uniprot ID:ACRO_HUMAN; ENSEMBL ID: ENSG00000100312; HGNC ID: 126
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005634IDA-nucleus21630459
GO:0005798IEA-Golgi-associated vesicle-
GO:0043159TAS-acrosomal matrix12398221
GO:0043234IDA-protein complex7521127
GO ID Evidence Qualifier GO_term References
GO:0002020TAS-protease binding-
GO:0003677NAS-DNA binding1937464
GO:0004040ISS-amidase activity-
GO:0004252IDA-serine-type endopeptidase activity6802470
GO:0005507NAS-copper ion binding6815104
GO:0005515IPI-protein binding7521127
GO:0005537IDA-mannose binding15950652
GO:0008144ISS-drug binding-
GO:0008270NAS-zinc ion binding6815104
GO:0042806ISS-fucose binding-
GO ID Evidence Qualifier GO_term References
GO:0002077NAS-acrosome matrix dispersal10418103
GO:0007190IDA-activation of adenylate cyclase activity3880736
GO:0007338ISS-single fertilization-
GO:0007339IEA-binding of sperm to zona pellucida-
GO:0007340IMP-acrosome reaction2550339
GO:0007340TAS-acrosome reaction-
GO:0007341IDANOTpenetration of zona pellucida10369396
GO:0048545IEA-response to steroid hormone-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SERPINA5ACR1111357521127 Reconstituted Complex
SERPINA5ACR1065657521127 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:87884
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018