AutismKB 2.0

Annotation Details for NTF3


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Basic Information Top
Gene Symbol:NTF3 ( HDNF,MGC129711,NGF-2,NGF2,NT3 )
Gene Full Name: neurotrophin 3
Band: 12p13.31
Quick LinksEntrez ID:4908; OMIM: 162660; Uniprot ID:NTF3_HUMAN; ENSEMBL ID: ENSG00000185652; HGNC ID: 8023
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576IBA-extracellular region-
GO:0031410IBA-cytoplasmic vesicle-
GO ID Evidence Qualifier GO_term References
GO:0005102TAS-receptor binding2236018
GO:0005166IBA-neurotrophin p75 receptor binding-
GO:0008083IDA-growth factor activity23027130
GO:0042056IDA-chemoattractant activity23027130
GO ID Evidence Qualifier GO_term References
GO:0000187IDA-activation of MAPK activity23027130
GO:0002092IDA-positive regulation of receptor internalization23027130
GO:0007165TAS-signal transduction2236018
GO:0007169IDA-transmembrane receptor protein tyrosine kinase signaling pathway23027130
GO:0007267TAS-cell-cell signaling2236018
GO:0007399TAS-nervous system development1542658
GO:0008284IDA-positive regulation of cell proliferation23027130
GO:0030335IDA-positive regulation of cell migration23027130
GO:0032148IDA-activation of protein kinase B activity23027130
GO:0033138IDA-positive regulation of peptidyl-serine phosphorylation23027130
GO:0042981IGI-regulation of apoptotic process23954828
GO:0043524IBA-negative regulation of neuron apoptotic process-
GO:0045664IBA-regulation of neuron differentiation-
GO:0048812IBA-neuron projection morphogenesis-
GO:0050731IDA-positive regulation of peptidyl-tyrosine phosphorylation23027130
GO:0050732IDA-negative regulation of peptidyl-tyrosine phosphorylation23027130
GO:0050918IEA-positive chemotaxis-
GO:0050930IDA-induction of positive chemotaxis23027130
GO:0090630IDA-activation of GTPase activity23027130
GO:2000251IDA-positive regulation of actin cytoskeleton reorganization23027130
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NTRK1NTF31109638621424 Reconstituted Complex
NTRK1NTF31109698621424 Reconstituted Complex
NTRK2NTF31109638621424 Reconstituted Complex
NTRK2NTF31109708621424 Reconstituted Complex
NTRK3NTF31109638621424 Reconstituted Complex
NTRK3NTF31109718621424 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
NTF3NTF3_1232A/C, NTF3_1531A/G, NTF3_2669C/G, NTF3_2768G/A, NTF3_295G/A, NTF3_3004G/A, NTF3_652C/T, NTF3_Gly63Glu, NTF3_STR Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:97380
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-031118-66'