AutismKB 2.0

Annotation Details for NTF4


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Basic Information Top
Gene Symbol:NTF4 ( GLC10,GLC1O,NT-4/5,NT4,NT5,NTF5 )
Gene Full Name: neurotrophin 4
Band: 19q13.3
Quick LinksEntrez ID:4909; OMIM: 162662; Uniprot ID:NTF4_HUMAN; ENSEMBL ID: ENSG00000167744; HGNC ID: 8024
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576IBA-extracellular region-
GO:0005576ISS-extracellular region10908605
GO:0005788ISS-endoplasmic reticulum lumen925010
GO:0031410IBA-cytoplasmic vesicle-
GO ID Evidence Qualifier GO_term References
GO:0005166IBA-neurotrophin p75 receptor binding-
GO:0005515IPI-protein binding25416956
GO:0008083IBA-growth factor activity-
GO ID Evidence Qualifier GO_term References
GO:0007169IBA-transmembrane receptor protein tyrosine kinase signaling pathway-
GO:0007267IBA-cell-cell signaling-
GO:0007402ISS-ganglion mother cell fate determination10681461
GO:0007616ISS-long-term memory10869436
GO:0008052ISS-sensory organ boundary specification10479455
GO:0008344ISS-adult locomotory behavior10681461
GO:0008544ISS-epidermis development9973328
GO:0042490IEA-mechanoreceptor differentiation-
GO:0043524IBA-negative regulation of neuron apoptotic process-
GO:0045664IBA-regulation of neuron differentiation-
GO:0048812IBA-neuron projection morphogenesis-
GO:0060384IEA-innervation-
GO:0061193IEA-taste bud development-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NTRK2NTF411096411855816 Reconstituted Complex
NTRK2NTF411097011855816 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:97381
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018