AutismKB 2.0

Annotation Details for ROR2


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Basic Information Top
Gene Symbol:ROR2 ( BDB,BDB1,MGC163394,NTRKR2 )
Gene Full Name: receptor tyrosine kinase-like orphan receptor 2
Band: 9q22.31
Quick LinksEntrez ID:4920; OMIM: 602337; Uniprot ID:ROR2_HUMAN; ENSEMBL ID: ENSG00000169071; HGNC ID: 10257
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005874IEA-microtubule-
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane1334494
GO:0009986IEA-cell surface-
GO:0030425IEA-dendrite-
GO:0030669TAS-clathrin-coated endocytic vesicle membrane-
GO:0043025IEA-neuronal cell body-
GO ID Evidence Qualifier GO_term References
GO:0004714IEA-transmembrane receptor protein tyrosine kinase activity-
GO:0005109IEA-frizzled binding-
GO:0005515IPI-protein binding22939624
GO:0005524IEA-ATP binding-
GO:0017147IPI-Wnt-protein binding19486338
GO:0046872IEA-metal ion binding-
GO:1904929TAS-coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway24431302
GO ID Evidence Qualifier GO_term References
GO:0001502IEA-cartilage condensation-
GO:0001756IEA-somitogenesis-
GO:0007165TAS-signal transduction1334494
GO:0007169IEA-transmembrane receptor protein tyrosine kinase signaling pathway-
GO:0007223IEA-Wnt signaling pathway, calcium modulating pathway-
GO:0007224IEA-smoothened signaling pathway-
GO:0007254IEA-JNK cascade-
GO:0007275TAS-multicellular organism development1334494
GO:0008285IMP-negative regulation of cell proliferation19486338
GO:0014002IEA-astrocyte development-
GO:0018108IEA-peptidyl-tyrosine phosphorylation-
GO:0030282IEA-bone mineralization-
GO:0030335IDA-positive regulation of cell migration19486338
GO:0030509IEA-BMP signaling pathway-
GO:0030538IEA-embryonic genitalia morphogenesis-
GO:0030539IEA-male genitalia development-
GO:0042472IEA-inner ear morphogenesis-
GO:0042733IEA-embryonic digit morphogenesis-
GO:0043507IEA-positive regulation of JUN kinase activity-
GO:0045165IEA-cell fate commitment-
GO:0045651IEA-positive regulation of macrophage differentiation-
GO:0045893IEA-positive regulation of transcription, DNA-templated-
GO:0051968IEA-positive regulation of synaptic transmission, glutamatergic-
GO:0060071TAS-Wnt signaling pathway, planar cell polarity pathway-
GO:0060395IEA-SMAD protein signal transduction-
GO:0090090IEA-negative regulation of canonical Wnt signaling pathway-
GO:0090263IEA-positive regulation of canonical Wnt signaling pathway-
GO:1900020IEA-positive regulation of protein kinase C activity-
GO:1905517IEA-macrophage migration-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MAGED1ROR211487912754255 Affinity Capture-Western
MAGED1ROR211097412754255 Affinity Capture-Western
IKBKGROR211097420098747 Reconstituted Complex
IKBKGROR211408920098747 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1347521
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060427-5'