AutismKB 2.0

Annotation Details for OAS3


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Basic Information Top
Gene Symbol:OAS3 ( MGC133260,p100 )
Gene Full Name: 2'-5'-oligoadenylate synthetase 3, 100kDa
Band: 12q24.13
Quick LinksEntrez ID:4940; OMIM: 603351; Uniprot ID:OAS3_HUMAN; ENSEMBL ID: ENSG00000111331; HGNC ID: 8088
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005615IDA-extracellular space23580065
GO:0005654IDA-nucleoplasm-
GO:0005737IDA-cytoplasm9880533
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane-
GO:0043231TAS-intracellular membrane-bounded organelle2440675
GO ID Evidence Qualifier GO_term References
GO:0001730IDA-2'-5'-oligoadenylate synthetase activity9880533
GO:0003725IDA-double-stranded RNA binding9880533
GO:0005515IPI-protein binding21903422
GO:0005524IDA-ATP binding9880533
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0006139TAS-nucleobase-containing compound metabolic process2440675
GO:0009615IDA-response to virus19056102
GO:0045071IDA-negative regulation of viral genome replication19056102
GO:0051607IDA-defense response to virus19923450
GO:0060333TAS-interferon-gamma-mediated signaling pathway-
GO:0060337TAS-type I interferon signaling pathway-
GO:0060700IDA-regulation of ribonuclease activity19923450
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2180850
  • Data Attributes: MGI curated and HomoloGene calculated
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018