AutismKB 2.0

Annotation Details for OGG1


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Basic Information Top
Gene Symbol:OGG1 ( HMMH,HOGG1,MUTM,OGH1 )
Gene Full Name: 8-oxoguanine DNA glycosylase
Band: 3p25.3
Quick LinksEntrez ID:4968; OMIM: 601982; Uniprot ID:OGG1_HUMAN; ENSEMBL ID: ENSG00000114026; HGNC ID: 8125
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus19506022
GO:0005654IDA-nucleoplasm17148573
GO:0005654TAS-nucleoplasm-
GO:0005739IEA-mitochondrion-
GO:0016363IDA-nuclear matrix17148573
GO:0016607IDA-nuclear speck17148573
GO:0043234IDA-protein complex19506022
GO ID Evidence Qualifier GO_term References
GO:0003684IDA-damaged DNA binding14706345
GO:0003906IEA-DNA-(apurinic or apyrimidinic site) lyase activity-
GO:0004519TAS-endonuclease activity9223305
GO:0005515IPI-protein binding15518571
GO:0008017IEA-microtubule binding-
GO:0008534TAS-oxidized purine nucleobase lesion DNA N-glycosylase activity-
GO:0019104IBA-DNA N-glycosylase activity-
GO:0032357IDA-oxidized purine DNA binding14706345
GO:0034039IEA-8-oxo-7,8-dihydroguanine DNA N-glycosylase activity-
GO ID Evidence Qualifier GO_term References
GO:0002526IEA-acute inflammatory response-
GO:0006284TAS-base-excision repair9190902
GO:0006355IMP-regulation of transcription, DNA-templated8621488
GO:0006974IGI-cellular response to DNA damage stimulus19506022
GO:0006979IDA-response to oxidative stress17148573
GO:0007568IEA-aging-
GO:0009314IDA-response to radiation17148573
GO:0009416IEA-response to light stimulus-
GO:0032355IEA-response to estradiol-
GO:0033158IDA-regulation of protein import into nucleus, translocation17148573
GO:0033683IDA-nucleotide-excision repair, DNA incision19506022
GO:0042493IEA-response to drug-
GO:0043066IEA-negative regulation of apoptotic process-
GO:0045007TAS-depurination-
GO:0045008TAS-depyrimidination-
GO:0045471IEA-response to ethanol-
GO:0051593IEA-response to folic acid-
GO:0071276IEA-cellular response to cadmium ion-
GO:1901291IDA-negative regulation of double-strand break repair via single-strand annealing19506022
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
OGG1CHGB11101816169070 Two-hybrid
OGG1CHGB10753916169070 Two-hybrid
PRKCAOGG111101812034821 Affinity Capture-Western; Biochemical Activity
PRKCAOGG111156412034821 Affinity Capture-Western; Biochemical Activity
XRCC1OGG111101812933815 Reconstituted Complex; Two-hybrid
XRCC1OGG111334912933815 Reconstituted Complex; Two-hybrid
SNRPFOGG111252017353931 Affinity Capture-MS
SNRPFOGG111101817353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
OGG1rs1052133 Gene overview in AlzGene
Gene Symbol Poly Names Gene overview in PDGene
OGG1rs1052133 Gene overview in PDGene
Gene Symbol Poly Names Gene overview in SZGene
OGG1rs1052133 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1097693
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070112-932'