AutismKB 2.0

Annotation Details for OPHN1


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Basic Information Top
Gene Symbol:OPHN1 ( ARHGAP41,MRX60,OPN1 )
Gene Full Name: oligophrenin 1
Band: Xq12
Quick LinksEntrez ID:4983; OMIM: 300127; Uniprot ID:OPHN1_HUMAN; ENSEMBL ID: ENSG00000079482; HGNC ID: 8148
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0015629IEA-actin cytoskeleton-
GO:0030054IEA-cell junction-
GO:0043195IEA-terminal bouton-
GO:0043197IEA-dendritic spine-
GO ID Evidence Qualifier GO_term References
GO:0003779IEA-actin binding-
GO:0005096TAS-GTPase activator activity-
GO:0005543IDA-phospholipid binding18954304
GO:0035255IEA-ionotropic glutamate receptor binding-
GO ID Evidence Qualifier GO_term References
GO:0006930TAS-substrate-dependent cell migration, cell extension9582072
GO:0007165IEA-signal transduction-
GO:0007399TAS-nervous system development9582072
GO:0007411TAS-axon guidance9582072
GO:0030036IEA-actin cytoskeleton organization-
GO:0030100IEA-regulation of endocytosis-
GO:0043547IEA-positive regulation of GTPase activity-
GO:0048488IEA-synaptic vesicle endocytosis-
GO:0051056TAS-regulation of small GTPase mediated signal transduction-
GO:0051966IEA-regulation of synaptic transmission, glutamatergic-
GO:1901799IEA-negative regulation of proteasomal protein catabolic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
OPHN1RHOA1068809582072 Biochemical Activity
OPHN1RHOA1110299582072 Biochemical Activity
OPHN1CDC421110299582072 Biochemical Activity
OPHN1CDC421074339582072 Biochemical Activity
RAC1OPHN11110299582072 Biochemical Activity
RAC1OPHN11118179582072 Biochemical Activity
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2151070
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040718-464'