AutismKB 2.0

Annotation Details for OPRK1


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Basic Information Top
Gene Symbol:OPRK1 ( KOR,OPRK )
Gene Full Name: opioid receptor, kappa 1
Band: 8q11.23
Quick LinksEntrez ID:4986; OMIM: 165196; Uniprot ID:OPRK_HUMAN; ENSEMBL ID: ENSG00000082556; HGNC ID: 8154
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0005887IMP-integral component of plasma membrane7624359
GO:0016021IDA-integral component of membrane22437504
GO:0030425IEA-dendrite-
GO:0043005IBA-neuron projection-
GO:0043204IEA-perikaryon-
GO:0043679IEA-axon terminus-
GO ID Evidence Qualifier GO_term References
GO:0004985IDA-opioid receptor activity22437504
GO:0005515IPI-protein binding16431922
GO:0038048IDA-dynorphin receptor activity8755601
GO:0038048IMP-dynorphin receptor activity7624359
GO:0042923IBA-neuropeptide binding-
GO ID Evidence Qualifier GO_term References
GO:0006955IDA-immune response8755601
GO:0007193TAS-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway7624359
GO:0007200ISS-phospholipase C-activating G-protein coupled receptor signaling pathway-
GO:0007218IBA-neuropeptide signaling pathway-
GO:0007268TAS-chemical synaptic transmission7624359
GO:0007600TAS-sensory perception7624359
GO:0007610TAS-behavior7624359
GO:0007626ISS-locomotory behavior-
GO:0009314IEA-response to radiation-
GO:0019233IBA-sensory perception of pain-
GO:0019233ISS-sensory perception of pain-
GO:0031635IDA-adenylate cyclase-inhibiting opioid receptor signaling pathway22437504
GO:0032868IEA-response to insulin-
GO:0033603IEA-positive regulation of dopamine secretion-
GO:0033685IEA-negative regulation of luteinizing hormone secretion-
GO:0038003IDA-opioid receptor signaling pathway8755601
GO:0040017IEA-positive regulation of locomotion-
GO:0042711IEA-maternal behavior-
GO:0042755IEA-eating behavior-
GO:0043278IEA-response to morphine-
GO:0043627IEA-response to estrogen-
GO:0044849IEA-estrous cycle-
GO:0045471IEA-response to ethanol-
GO:0046877ISS-regulation of saliva secretion-
GO:0048148IEA-behavioral response to cocaine-
GO:0050951IEA-sensory perception of temperature stimulus-
GO:0051607IDA-defense response to virus8755601
GO:0051930IEA-regulation of sensory perception of pain-
GO:0071222IEA-cellular response to lipopolysaccharide-
GO:1900745IEA-positive regulation of p38MAPK cascade-
GO:1901381IEA-positive regulation of potassium ion transmembrane transport-
GO:1903715IEA-regulation of aerobic respiration-
GO:1903937IEA-response to acrylamide-
GO:1990708IEA-conditioned place preference-
GO:2000505IEA-regulation of energy homeostasis-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SLC9A3R1OPRK111476912004055 15070904 Affinity Capture-Western; Reconstituted Complex
SLC9A3R1OPRK111103112004055 15070904 Affinity Capture-Western; Reconstituted Complex
UBCOPRK111316418212250 Affinity Capture-Western
UBCOPRK111103118212250 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:97439
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030729-1'