AutismKB 2.0

Annotation Details for OPRL1


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Basic Information Top
Gene Symbol:OPRL1 ( KOR-3,MGC34578,NOCIR,OOR,ORL1 )
Gene Full Name: opiate receptor-like 1
Band: 20q13.33
Quick LinksEntrez ID:4987; OMIM: 602548; Uniprot ID:OPRX_HUMAN; ENSEMBL ID: ENSG00000125510; HGNC ID: 8155
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0005887IDA-integral component of plasma membrane8137918
GO:0031410IEA-cytoplasmic vesicle-
GO:0043005IBA-neuron projection-
GO ID Evidence Qualifier GO_term References
GO:0001626IDA-nociceptin receptor activity12568343
GO:0004930IGI-G-protein coupled receptor activity10571060
GO:0004930IMP-G-protein coupled receptor activity8137918
GO:0005515IPI-protein binding23597562
GO:0008022IEA-protein C-terminus binding-
GO:0042923IBA-neuropeptide binding-
GO ID Evidence Qualifier GO_term References
GO:0001934IEA-positive regulation of protein phosphorylation-
GO:0007193IMP-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway8137918
GO:0007204IGI-positive regulation of cytosolic calcium ion concentration10571060
GO:0007218IBA-neuropeptide signaling pathway-
GO:0007268IBA-chemical synaptic transmission-
GO:0007600TAS-sensory perception7566152
GO:0019233IBA-sensory perception of pain-
GO:0019233ISS-sensory perception of pain-
GO:0030818IEA-negative regulation of cAMP biosynthetic process-
GO:0032355IEA-response to estradiol-
GO:0035810IEA-positive regulation of urine volume-
GO:0038003IEA-opioid receptor signaling pathway-
GO:0042755IEA-eating behavior-
GO:0044849IEA-estrous cycle-
GO:0045776IEA-negative regulation of blood pressure-
GO:0060454IEA-positive regulation of gastric acid secretion-
GO:1901386IEA-negative regulation of voltage-gated calcium channel activity-
GO:1904058IEA-positive regulation of sensory perception of pain-
GO:1904059IEA-regulation of locomotor rhythm-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PNOCOPRL111138110692489 11097863 Reconstituted Complex
PNOCOPRL111103210692489 11097863 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:97440
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040312-4'