AutismKB 2.0

Annotation Details for OTC


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Basic Information Top
Gene Symbol:OTC ( MGC129967,MGC129968,MGC138856,OCTD )
Gene Full Name: ornithine carbamoyltransferase
Band: Xp11.4
Quick LinksEntrez ID:5009; OMIM: 300461; Uniprot ID:OTC_HUMAN; ENSEMBL ID: ENSG00000036473; HGNC ID: 8512
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005739IDA-mitochondrion3472484
GO:0005743IEA-mitochondrial inner membrane-
GO:0005759NAS-mitochondrial matrix6372096
GO:0005759TAS-mitochondrial matrix-
GO ID Evidence Qualifier GO_term References
GO:0004585EXP-ornithine carbamoyltransferase activity6372096
GO:0004585IDA-ornithine carbamoyltransferase activity2556444
GO:0005543IEA-phospholipid binding-
GO:0016597IEA-amino acid binding-
GO:0042301IEA-phosphate ion binding-
GO ID Evidence Qualifier GO_term References
GO:0000050IDA-urea cycle2556444
GO:0000050IEA-urea cycle-
GO:0000050TAS-urea cycle-
GO:0001889IEA-liver development-
GO:0006526IEA-arginine biosynthetic process-
GO:0006593IDA-ornithine catabolic process2556444
GO:0007494IEA-midgut development-
GO:0010043IEA-response to zinc ion-
GO:0019240IDA-citrulline biosynthetic process2556444
GO:0032868IEA-response to insulin-
GO:0042493IEA-response to drug-
GO:0055081IEA-anion homeostasis-
GO:0070207IEA-protein homotrimerization-
GO:0070781IEA-response to biotin-
GO:0097272IMP-ammonia homeostasis2556444
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TOMM20OTC1110509756929 Reconstituted Complex
TOMM20OTC1151449756929 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
OTCrs5963409, rs5963411 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:97448
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070912-422'