AutismKB 2.0

Annotation Details for P2RX1


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Basic Information Top
Gene Symbol:P2RX1 ( P2X1 )
Gene Full Name: purinergic receptor P2X, ligand-gated ion channel, 1
Band: 17p13.3
Quick LinksEntrez ID:5023; OMIM: 600845; Uniprot ID:P2RX1_HUMAN; ENSEMBL ID: ENSG00000108405; HGNC ID: 8533
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005639IBA-integral component of nuclear inner membrane-
GO:0005886TAS-plasma membrane-
GO:0005887IEA-integral component of plasma membrane-
GO:0030667TAS-secretory granule membrane-
GO:0035579TAS-specific granule membrane-
GO:0043005IEA-neuron projection-
GO:0043234IEA-protein complex-
GO:0045121IEA-membrane raft-
GO:0045211IEA-postsynaptic membrane-
GO ID Evidence Qualifier GO_term References
GO:0001614IDA-purinergic nucleotide receptor activity8834001
GO:0004931IBA-extracellular ATP-gated cation channel activity-
GO:0005261IDA-cation channel activity8834001
GO:0005524IEA-ATP binding-
GO:0008144IEA-drug binding-
GO:0008270IEA-zinc ion binding-
GO ID Evidence Qualifier GO_term References
GO:0002554IEA-serotonin secretion by platelet-
GO:0003056IEA-regulation of vascular smooth muscle contraction-
GO:0006810TAS-transport9565569
GO:0006811IDA-ion transport8834001
GO:0006915IEA-apoptotic process-
GO:0006919IEA-activation of cysteine-type endopeptidase activity involved in apoptotic process-
GO:0007165TAS-signal transduction9565569
GO:0007320IEA-insemination-
GO:0007596TAS-blood coagulation-
GO:0008217IEA-regulation of blood pressure-
GO:0019228IEA-neuronal action potential-
GO:0030168IEA-platelet activation-
GO:0033198IEA-response to ATP-
GO:0035249IEA-synaptic transmission, glutamatergic-
GO:0035590IEA-purinergic nucleotide receptor signaling pathway-
GO:0042310IEA-vasoconstriction-
GO:0043270IEA-positive regulation of ion transport-
GO:0043312TAS-neutrophil degranulation-
GO:0046513IEA-ceramide biosynthetic process-
GO:0051260IEA-protein homooligomerization-
GO:0051291IEA-protein heterooligomerization-
GO:0051924IEA-regulation of calcium ion transport-
GO:0060079IEA-excitatory postsynaptic potential-
GO:0098655IEA-cation transmembrane transport-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1098235
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030319-1'