Gene Symbol:	NOX4 ( KOX,KOX-1,RENOX )
Gene Full Name:	NADPH oxidase 4
Band:	11q14.3
Quick Links	Entrez ID:50507; OMIM: 605261; Uniprot ID:NOX4_HUMAN; ENSEMBL ID: ENSG00000086991; HGNC ID: 7891
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0001725	IEA	-	stress fiber	-
GO:0005634	IDA	-	nucleus	-
GO:0005730	IEA	-	nucleolus	-
GO:0005739	IEA	-	mitochondrion	-
GO:0005789	TAS	-	endoplasmic reticulum membrane	-
GO:0005925	IEA	-	focal adhesion	-
GO:0016021	TAS	-	integral component of membrane	10869423
GO:0016324	IEA	-	apical plasma membrane	-
GO:0043020	IEA	-	NADPH oxidase complex	-
GO:0048471	IEA	-	perinuclear region of cytoplasm	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0000166	TAS	-	nucleotide binding	10869423
GO:0005515	IPI	-	protein binding	15356101
GO:0009055	TAS	-	electron carrier activity	10869423
GO:0016174	TAS	-	NAD(P)H oxidase activity	10869423
GO:0016175	TAS	-	superoxide-generating NADPH oxidase activity	-
GO:0019826	TAS	-	oxygen sensor activity	10869423
GO:0020037	TAS	-	heme binding	10869423
GO:0050660	TAS	-	flavin adenine dinucleotide binding	10869423
GO:0072341	IDA	-	modified amino acid binding	20031578

GO ID	Evidence	Qualifier	GO_term	References
GO:0000902	ISS	-	cell morphogenesis	10869423
GO:0001666	IEA	-	response to hypoxia	-
GO:0006801	IDA	-	superoxide metabolic process	18760347
GO:0006954	TAS	-	inflammatory response	10869423
GO:0007569	ISS	-	cell aging	10869423
GO:0008285	ISS	-	negative regulation of cell proliferation	10869423
GO:0010467	IMP	-	gene expression	23144758
GO:0014911	IEA	-	positive regulation of smooth muscle cell migration	-
GO:0034599	TAS	-	cellular response to oxidative stress	-
GO:0042554	ISS	-	superoxide anion generation	10869423
GO:0043065	IEA	-	positive regulation of apoptotic process	-
GO:0043406	IEA	-	positive regulation of MAP kinase activity	-
GO:0045453	IEA	-	bone resorption	-
GO:0050667	IDA	-	homocysteine metabolic process	20031578
GO:0051496	IEA	-	positive regulation of stress fiber assembly	-
GO:0051897	IEA	-	positive regulation of protein kinase B signaling	-
GO:0055007	IEA	-	cardiac muscle cell differentiation	-
GO:0055114	IDA	-	oxidation-reduction process	10869423
GO:0070374	IEA	-	positive regulation of ERK1 and ERK2 cascade	-
GO:0071320	IEA	-	cellular response to cAMP	-
GO:0071333	IEA	-	cellular response to glucose stimulus	-
GO:0071480	IEA	-	cellular response to gamma radiation	-
GO:0071560	IEA	-	cellular response to transforming growth factor beta stimulus	-
GO:0072593	IDA	-	reactive oxygen species metabolic process	10869423
GO:2000379	IEA	-	positive regulation of reactive oxygen species metabolic process	-
GO:2000573	IEA	-	positive regulation of DNA biosynthetic process	-

AutismKB 2.0

Annotation Details for NOX4