AutismKB 2.0

Annotation Details for ITSN2


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Basic Information Top
Gene Symbol:ITSN2 ( KIAA1256,PRO2015,SH3D1B,SH3P18,SWA,SWAP )
Gene Full Name: intersectin 2
Band: 2p23.3
Quick LinksEntrez ID:50618; OMIM: 604464; Uniprot ID:ITSN2_HUMAN; ENSEMBL ID: ENSG00000198399; HGNC ID: 6184
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IEA-cytoplasm-
GO:0005813IDA-centrosome20479469
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0005070TAS-SH3/SH2 adaptor activity9630982
GO:0005089IEA-Rho guanyl-nucleotide exchange factor activity-
GO:0005509IEA-calcium ion binding-
GO:0005515IPI-protein binding17696407
GO ID Evidence Qualifier GO_term References
GO:0006897IEA-endocytosis-
GO:0009967IEA-positive regulation of signal transduction-
GO:0035023IEA-regulation of Rho protein signal transduction-
GO:0043547IEA-positive regulation of GTPase activity-
GO:1903861IDA-positive regulation of dendrite extension23999003
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ITSN2PTN11909816169070 Two-hybrid
ITSN2PTN11173116169070 Two-hybrid
ITSN2SOS111253720936779 Two-hybrid
ITSN2SOS111909820936779 Two-hybrid
ITSN2WAS11909811748279 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ITSN2WAS11329311748279 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ITSN2MAP4K311406320936779 Two-hybrid
ITSN2MAP4K311909820936779 Two-hybrid
ITSN2TBL311909816169070 Two-hybrid
ITSN2TBL311585316169070 Two-hybrid
ITSN2SRGAP211909819041431 Affinity Capture-MS
ITSN2SRGAP211695619041431 Affinity Capture-MS
NAA38ITSN211909815231747 Two-hybrid
NAA38ITSN211967915231747 Two-hybrid
BCCIPITSN211909816169070 Two-hybrid
BCCIPITSN212116116169070 Two-hybrid
FCHSD1ITSN211909819041431 Affinity Capture-MS
FCHSD1ITSN212461919041431 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1338049
  • Data Attributes: HomoloGene calculated
No data