Gene Symbol:	PAM ( PAL,PHM )
Gene Full Name:	peptidylglycine alpha-amidating monooxygenase
Band:	5q21.1
Quick Links	Entrez ID:5066; OMIM: 170270; Uniprot ID:AMD_HUMAN; ENSEMBL ID: ENSG00000145730; HGNC ID: 8596
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0005615	IEA	-	extracellular space	-
GO:0005802	IEA	-	trans-Golgi network	-
GO:0005886	IEA	-	plasma membrane	-
GO:0009986	IEA	-	cell surface	-
GO:0016020	IDA	-	membrane	19946888
GO:0016021	IEA	-	integral component of membrane	-
GO:0030667	IEA	-	secretory granule membrane	-
GO:0043005	IEA	-	neuron projection	-
GO:0043204	IEA	-	perikaryon	-
GO:0048471	IEA	-	perinuclear region of cytoplasm	-
GO:0070062	IDA	-	extracellular exosome	19199708

GO ID	Evidence	Qualifier	GO_term	References
GO:0004504	IDA	-	peptidylglycine monooxygenase activity	2357221
GO:0004598	IDA	-	peptidylamidoglycolate lyase activity	12699694
GO:0005507	IEA	-	copper ion binding	-
GO:0005509	IEA	-	calcium ion binding	-
GO:0005515	IPI	-	protein binding	9837933
GO:0008270	IDA	-	zinc ion binding	12699694
GO:0019901	IEA	-	protein kinase binding	-
GO:0031418	IEA	-	L-ascorbic acid binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0001519	IDA	-	peptide amidation	2357221
GO:0001666	IEA	-	response to hypoxia	-
GO:0001676	IEA	-	long-chain fatty acid metabolic process	-
GO:0006357	IEA	-	regulation of transcription from RNA polymerase II promoter	-
GO:0007417	IEA	-	central nervous system development	-
GO:0007507	IEA	-	heart development	-
GO:0007595	IEA	-	lactation	-
GO:0009268	IEA	-	response to pH	-
GO:0009404	IEA	-	toxin metabolic process	-
GO:0018032	IEA	-	protein amidation	-
GO:0022602	IEA	-	ovulation cycle process	-
GO:0032355	IEA	-	response to estradiol	-
GO:0032956	IEA	-	regulation of actin cytoskeleton organization	-
GO:0042476	IEA	-	odontogenesis	-
GO:0042493	IEA	-	response to drug	-
GO:0046688	IEA	-	response to copper ion	-
GO:0050708	IEA	-	regulation of protein secretion	-
GO:0051260	IEA	-	protein homooligomerization	-
GO:0051384	IEA	-	response to glucocorticoid	-
GO:0055114	IEA	-	oxidation-reduction process	-
GO:0060135	IEA	-	maternal process involved in female pregnancy	-
GO:0060173	IEA	-	limb development	-

Gene Symbol	Interactant	Interaction ID	References	Description
KALRN	PAM	114478	9139723	Two-hybrid
KALRN	PAM	111101	9139723	Two-hybrid
RASSF9	PAM	111101	9837933	Reconstituted Complex; Two-hybrid
RASSF9	PAM	114619	9837933	Reconstituted Complex; Two-hybrid
TSC2	PAM	111101	14559897	Affinity Capture-Western; Co-localization; Two-hybrid
TSC2	PAM	113100	14559897	Affinity Capture-Western; Co-localization; Two-hybrid
TSC1	PAM	111101	14559897	Co-localization
TSC1	PAM	113099	14559897	Co-localization

AutismKB 2.0

Annotation Details for PAM