AutismKB 2.0

Annotation Details for ASAP1


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Basic Information Top
Gene Symbol:ASAP1 ( AMAP1,CENTB4,DDEF1,KIAA1249,PAG2,PAP,ZG14P )
Gene Full Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
Band: 8q24.21-q24.22
Quick LinksEntrez ID:50807; OMIM: 605953; Uniprot ID:ASAP1_HUMAN; ENSEMBL ID: ENSG00000153317; HGNC ID: 2720
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0002102IEA-podosome-
GO:0005829TAS-cytosol-
GO:0031253IEA-cell projection membrane-
GO:0043197IEA-dendritic spine-
GO ID Evidence Qualifier GO_term References
GO:0001786IEA-phosphatidylserine binding-
GO:0005096IEA-GTPase activator activity-
GO:0005515IPI-protein binding12029088
GO:0005546IEA-phosphatidylinositol-4,5-bisphosphate binding-
GO:0005547IEA-phosphatidylinositol-3,4,5-trisphosphate binding-
GO:0045296IDA-cadherin binding25468996
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0043547IEA-positive regulation of GTPase activity-
GO:0060271IMP-cilium assembly20393563
GO:0061000IEA-negative regulation of dendritic spine development-
GO:0071803IEA-positive regulation of podosome assembly-
GO:1903527IEA-positive regulation of membrane tubulation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ASAP1CRK1191269819391 Reconstituted Complex
ASAP1CRK1077889819391 Reconstituted Complex
ASAP1GRB211912620936779 Two-hybrid
ASAP1GRB210914220936779 Two-hybrid
ASAP1PXN11178712149250 Reconstituted Complex
ASAP1PXN11912612149250 Reconstituted Complex
ASAP1SRC1125929819391 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ASAP1SRC1191269819391 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ASAP1TRIP1011473319041431 Affinity Capture-MS
ASAP1TRIP1011912619041431 Affinity Capture-MS
ASAP1PACSIN211912619041431 Affinity Capture-MS
ASAP1PACSIN211641319041431 Affinity Capture-MS
ASAP1PACSIN311912619041431 Affinity Capture-MS
ASAP1PACSIN311889619041431 Affinity Capture-MS
ASAP1PACSIN111912619041431 Affinity Capture-MS
ASAP1PACSIN111901819041431 Affinity Capture-MS
FCHSD1ASAP112461919041431 Affinity Capture-MS
FCHSD1ASAP111912619041431 Affinity Capture-MS
Gene Symbol Interactant Interaction ID References Description
ASAP1CRK21790915719014 DDEF1 (AMAP1) interacts with an unspecified isoform of CRK (Crk II).
ASAP1CTTN21790815719014 DDEF1 (AMAP1) interacts with an unspecified isoform of CTTN (cortactin).
ASAP1ITSN121791115719014 DDEF1 (AMAP1) interacts with an unspecified isoform of ITSN1 (Intersectin1).
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1342335
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-091112-16'