AutismKB 2.0

Annotation Details for PBX1


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Basic Information Top
Gene Symbol:PBX1 ( DKFZp686B09108,MGC126627 )
Gene Full Name: pre-B-cell leukemia homeobox 1
Band: 1q23.3
Quick LinksEntrez ID:5087; OMIM: 176310; Uniprot ID:PBX1_HUMAN; ENSEMBL ID: ENSG00000185630; HGNC ID: 8632
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus18973687
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005667IEA-transcription factor complex-
GO:0005737IDA-cytoplasm18973687
GO ID Evidence Qualifier GO_term References
GO:0000978IEA-RNA polymerase II core promoter proximal region sequence-specific DNA binding-
GO:0001077IEA-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-
GO:0003677IDA-DNA binding10052460
GO:0003700NAS-transcription factor activity, sequence-specific DNA binding10500199
GO:0005515IPI-protein binding10052460
GO:0046982IEA-protein heterodimerization activity-
GO ID Evidence Qualifier GO_term References
GO:0001658IEA-branching involved in ureteric bud morphogenesis-
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0006694IEA-steroid biosynthetic process-
GO:0007548IEA-sex differentiation-
GO:0008284IEA-positive regulation of cell proliferation-
GO:0009952IEA-anterior/posterior pattern specification-
GO:0009954IEA-proximal/distal pattern formation-
GO:0010971IEA-positive regulation of G2/M transition of mitotic cell cycle-
GO:0030278IEA-regulation of ossification-
GO:0030325IEA-adrenal gland development-
GO:0030326IEA-embryonic limb morphogenesis-
GO:0035019TAS-somatic stem cell population maintenance-
GO:0035162IEA-embryonic hemopoiesis-
GO:0045665IEA-negative regulation of neuron differentiation-
GO:0045944IEA-positive regulation of transcription from RNA polymerase II promoter-
GO:0048536IEA-spleen development-
GO:0048538IEA-thymus development-
GO:0048706IEA-embryonic skeletal system development-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PBX1NR3C110916512487626 Affinity Capture-Western
PBX1NR3C111112012487626 Affinity Capture-Western
PBX1HDAC110931511046157 Affinity Capture-Western
PBX1HDAC111112011046157 Affinity Capture-Western
PBX1HOXA910944510082572 Reconstituted Complex
PBX1HOXA911112010082572 Reconstituted Complex
PBX1HOXA1010944614512427 Reconstituted Complex
PBX1HOXA1011112014512427 Reconstituted Complex
PBX1HOXB11094519482740 10052460 Co-crystal Structure; Reconstituted Complex
PBX1HOXB11111209482740 10052460 Co-crystal Structure; Reconstituted Complex
PBX1HOXB71094577729685 Reconstituted Complex; Two-hybrid
PBX1HOXB71111207729685 Reconstituted Complex; Two-hybrid
PBX1HOXB810945811571641 Reconstituted Complex
PBX1HOXB811112011571641 Reconstituted Complex
PBX1HOXD410947310523646 Reconstituted Complex
PBX1HOXD411112010523646 Reconstituted Complex
PBX1HOXD910947510523646 Reconstituted Complex
PBX1HOXD911112010523646 Reconstituted Complex
PBX1MEIS111037510082572 10373562 10523646 Reconstituted Complex
PBX1MEIS111112010082572 10373562 10523646 Reconstituted Complex
PBX1MEIS211037620211142 Two-hybrid
PBX1MEIS211112020211142 Two-hybrid
PBX1MYH1011071312724421 Affinity Capture-Western
PBX1MYH1011112012724421 Affinity Capture-Western
PBX1MYOD111073720195544 Affinity Capture-MS
PBX1MYOD111112020195544 Affinity Capture-MS
PKNOX1PBX11113339482740 Reconstituted Complex
PKNOX1PBX11111209482740 Reconstituted Complex
SIN3BPBX111690111046157 Affinity Capture-Western
SIN3BPBX111112011046157 Affinity Capture-Western
HDAC3PBX111436811046157 Affinity Capture-Western
HDAC3PBX111112011046157 Affinity Capture-Western
POU2F1PBX111144715138251 Reconstituted Complex
POU2F1PBX111112015138251 Reconstituted Complex
SMARCA4PBX111248115870273 Affinity Capture-Western
SMARCA4PBX111112015870273 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:97495
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-000405-1'