AutismKB 2.0

Annotation Details for SH3GLB1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SH3GLB1 ( Bif-1,KIAA0491,dJ612B15.2 )
Gene Full Name: SH3-domain GRB2-like endophilin B1
Band: 1p22.3
Quick LinksEntrez ID:51100; OMIM: 609287; Uniprot ID:SHLB1_HUMAN; ENSEMBL ID: ENSG00000097033; HGNC ID: 10833
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000139IEA-Golgi membrane-
GO:0000421IDA-autophagosome membrane17891140
GO:0005737IDA-cytoplasm11161816
GO:0005741IEA-mitochondrial outer membrane-
GO:0005829IDA-cytosol-
GO:0030496IDA-midbody20643123
GO:0031410IEA-cytoplasmic vesicle-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding11161816
GO:0008289IEA-lipid binding-
GO:0042802IPI-identical protein binding20562859
GO:0042803IPI-protein homodimerization activity11161816
GO:0045296IDA-cadherin binding25468996
GO ID Evidence Qualifier GO_term References
GO:0006914IEA-autophagy-
GO:0006915IEA-apoptotic process-
GO:0010508IMP-positive regulation of autophagy17891140
GO:0016241TAS-regulation of macroautophagy21499257
GO:0031647IMP-regulation of protein stability24270810
GO:0032461IDA-positive regulation of protein oligomerization19074440
GO:0032465IMP-regulation of cytokinesis20643123
GO:0032801IMP-receptor catabolic process20643123
GO:0034198IMP-cellular response to amino acid starvation21068542
GO:0042149IMP-cellular response to glucose starvation21068542
GO:0048102IMP-autophagic cell death17891140
GO:0051259IDA-protein oligomerization19805544
GO:0090148IMP-membrane fission21068542
GO:1903527IMP-positive regulation of membrane tubulation21068542
GO:1903778IMP-protein localization to vacuolar membrane21068542
GO:1903955IMP-positive regulation of protein targeting to mitochondrion24270810
GO:2000786IMP-positive regulation of autophagosome assembly21068542
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SH3GLB1AMPH11928912456676 Reconstituted Complex
SH3GLB1AMPH10677012456676 Reconstituted Complex
SH3GLB1BIN111928912456676 Reconstituted Complex
SH3GLB1BIN110677112456676 Reconstituted Complex
SH3GLB1BAX11928911161816 11259440 Affinity Capture-Western; Two-hybrid
SH3GLB1BAX10705711161816 11259440 Affinity Capture-Western; Two-hybrid
SH3GLB1DNM110809912456676 Reconstituted Complex
SH3GLB1DNM111928912456676 Reconstituted Complex
SH3GLB1HTT11928912456676 Reconstituted Complex
SH3GLB1HTT10931412456676 Reconstituted Complex
SH3GLB1USP711928920562859 Affinity Capture-MS
SH3GLB1USP711362220562859 Affinity Capture-MS
SH3GLB1CUL211403120562859 Affinity Capture-MS
SH3GLB1CUL211928920562859 Affinity Capture-MS
SH3GLB1KLHDC1011928920562859 Affinity Capture-MS
SH3GLB1KLHDC1011665220562859 Affinity Capture-MS
SH3GLB1SH3KBP111902911894096 Reconstituted Complex
SH3GLB1SH3KBP111928911894096 Reconstituted Complex
SH3GLB2SH3GLB112123411161816 20562859 Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
SH3GLB2SH3GLB111928911161816 20562859 Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
ARHGAP17SH3GLB111928911431473 Reconstituted Complex
ARHGAP17SH3GLB112042411431473 Reconstituted Complex
Gene Symbol Interactant Interaction ID References Description
SH3GLB1BAX20923211161816 An unspecified isoform of Bax interacts with SH3GLB1.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1859730
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-6851'