AutismKB 2.0

Annotation Details for PCSK5


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Basic Information Top
Gene Symbol:PCSK5 ( FLJ11149,FLJ16215,PC5,PC6,PC6A,SPC6 )
Gene Full Name: proprotein convertase subtilisin/kexin type 5
Band: 9q21.13
Quick LinksEntrez ID:5125; OMIM: 600488; Uniprot ID:PCSK5_HUMAN; ENSEMBL ID: ENSG00000099139; HGNC ID: 8747
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615ISS-extracellular space8940009
GO:0005794IDA-Golgi apparatus-
GO:0005794ISS-Golgi apparatus-
GO:0005796TAS-Golgi lumen-
GO:0016021IEA-integral component of membrane-
GO:0030141ISS-secretory granule-
GO ID Evidence Qualifier GO_term References
GO:0004175EXP-endopeptidase activity16109723
GO:0004252IDA-serine-type endopeptidase activity8901832
GO:0005515IPI-protein binding25416956
GO:0008233IDA-peptidase activity15606899
GO:0042277ISS-peptide binding8940009
GO ID Evidence Qualifier GO_term References
GO:0001822IMP-kidney development18519639
GO:0001822ISS-kidney development8940009
GO:0002001IEP-renin secretion into blood stream8901832
GO:0003279IEA-cardiac septum development-
GO:0006465IDA-signal peptide processing16912035
GO:0007267TAS-cell-cell signaling8901832
GO:0007368IEA-determination of left/right symmetry-
GO:0007507ISS-heart development8940009
GO:0007566ISS-embryo implantation8940009
GO:0009952IMP-anterior/posterior pattern specification18519639
GO:0016485IDA-protein processing8901832
GO:0016486IDA-peptide hormone processing8901832
GO:0019058IEP-viral life cycle8940009
GO:0019058ISS-viral life cycle8940009
GO:0030323ISS-respiratory tube development8940009
GO:0032455TAS-nerve growth factor processing-
GO:0035108ISS-limb morphogenesis8940009
GO:0042089ISS-cytokine biosynthetic process8940009
GO:0043043IDA-peptide biosynthetic process8901832
GO:0048566IMP-embryonic digestive tract development18519639
GO:0048566ISS-embryonic digestive tract development8940009
GO:0048706IMP-embryonic skeletal system development18519639
GO:0048706ISS-embryonic skeletal system development8940009
GO:0051004TAS-regulation of lipoprotein lipase activity-
GO:0060976IEA-coronary vasculature development-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
APPBP2PCSK511115216189514 Two-hybrid
APPBP2PCSK511576916189514 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:97515
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060531-130'