AutismKB 2.0

Annotation Details for FZR1


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Basic Information Top
Gene Symbol:FZR1 ( CDC20C,CDH1,FZR,FZR2,HCDH,HCDH1,KIAA1242 )
Gene Full Name: fizzy/cell division cycle 20 related 1 (Drosophila)
Band: 19p13.3
Quick LinksEntrez ID:51343; OMIM: 603619; Uniprot ID:FZR_HUMAN; ENSEMBL ID: ENSG00000105325; HGNC ID: 24824
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005680IDAcolocalizes_withanaphase-promoting complex11459825
GO:0005829TAS-cytosol-
GO:0031965IDA-nuclear membrane-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding11459826
GO:0010997IEA-anaphase-promoting complex binding-
GO:0097027IEA-ubiquitin-protein transferase activator activity-
GO ID Evidence Qualifier GO_term References
GO:0006281IEA-DNA repair-
GO:0008284IEA-positive regulation of cell proliferation-
GO:0031145IDA-anaphase-promoting complex-dependent catabolic process18662541
GO:0031145TAS-anaphase-promoting complex-dependent catabolic process-
GO:0031572IDA-G2 DNA damage checkpoint18662541
GO:0040020IEA-regulation of meiotic nuclear division-
GO:0042787TAS-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-
GO:0045732IGI-positive regulation of protein catabolic process11459825
GO:0051301IEA-cell division-
GO:0051436TAS-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-
GO:0051437TAS-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-
GO:0051439TAS-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-
GO:0070306IEA-lens fiber cell differentiation-
GO:0070979TAS-protein K11-linked ubiquitination21596315
GO:0090344IEA-negative regulation of cell aging-
GO:1904668IDA-positive regulation of ubiquitin protein ligase activity11459826
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FZR1CDC2011948916287863 Affinity Capture-Western
FZR1CDC2010742716287863 Affinity Capture-Western
FZR1CDC271194899811605 12097298 12797865 Affinity Capture-Western
FZR1CDC271074319811605 12097298 12797865 Affinity Capture-Western
FZR1SKIL11948911691834 Affinity Capture-Western
FZR1SKIL11238911691834 Affinity Capture-Western
FZR1CDC14A11948911598127 Biochemical Activity
FZR1CDC14A11412611598127 Biochemical Activity
FZR1MAD2L211948917719540 Affinity Capture-Western
FZR1MAD2L211572217719540 Affinity Capture-Western
FZR1TPX211948916287863 Affinity Capture-Western
FZR1TPX211662416287863 Affinity Capture-Western
FZR1FBXO511948911988738 Affinity Capture-Western; Reconstituted Complex
FZR1FBXO511765511988738 Affinity Capture-Western; Reconstituted Complex
FZR1ANAPC211948916287863 Affinity Capture-Western
FZR1ANAPC211893716287863 Affinity Capture-Western
FZR1ANAPC411948912956947 Reconstituted Complex
FZR1ANAPC411898212956947 Reconstituted Complex
ANAPC5FZR111948912956947 Reconstituted Complex
ANAPC5FZR111953712956947 Reconstituted Complex
ANAPC7FZR111948912956947 Reconstituted Complex
ANAPC7FZR111953812956947 Reconstituted Complex
ANAPC1FZR111948912956947 Reconstituted Complex
ANAPC1FZR112222912956947 Reconstituted Complex
CDT1FZR111948918162579 Affinity Capture-Western; Reconstituted Complex
CDT1FZR112355518162579 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1926790
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-712'