AutismKB 2.0

Annotation Details for UBR5


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Basic Information Top
Gene Symbol:UBR5 ( DD5,EDD,EDD1,FLJ11310,HYD,KIAA0896,MGC57263 )
Gene Full Name: ubiquitin protein ligase E3 component n-recognin 5
Band: 8q22.3
Quick LinksEntrez ID:51366; OMIM: 608413; Uniprot ID:UBR5_HUMAN; ENSEMBL ID: ENSG00000104517; HGNC ID: 16806
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus12011095
GO:0005654IDA-nucleoplasm-
GO:0005829IDA-cytosol-
GO:0016020IDA-membrane19946888
GO:0043234IDA-protein complex18076571
GO:0048471IDA-perinuclear region of cytoplasm18076571
GO ID Evidence Qualifier GO_term References
GO:0003723IEA-RNA binding-
GO:0004842TAS-ubiquitin-protein transferase activity10030672
GO:0005515IPI-protein binding12011095
GO:0008270IEA-zinc ion binding-
GO:0034450IDA-ubiquitin-ubiquitin ligase activity21118991
GO:0043130IEA-ubiquitin binding-
GO ID Evidence Qualifier GO_term References
GO:0000209IDA-protein polyubiquitination21118991
GO:0006281IEA-DNA repair-
GO:0006511TAS-ubiquitin-dependent protein catabolic process10030672
GO:0006974IDA-cellular response to DNA damage stimulus12011095
GO:0006974IMP-cellular response to DNA damage stimulus22884692
GO:0008283TAS-cell proliferation10030672
GO:0010628IDA-positive regulation of gene expression18076571
GO:0033160IMP-positive regulation of protein import into nucleus, translocation21118991
GO:0035413IMP-positive regulation of catenin import into nucleus21118991
GO:0050847IDA-progesterone receptor signaling pathway12011095
GO:0090263IMP-positive regulation of canonical Wnt signaling pathway21118991
GO:1901315IMP-negative regulation of histone H2A K63-linked ubiquitination22884692
GO:2000780IMP-negative regulation of double-strand break repair22884692
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
UBR5CEBPD10748120805509 Affinity Capture-MS
UBR5CEBPD11950120805509 Affinity Capture-MS
UBR5GTF2E210921617643375 Affinity Capture-MS
UBR5GTF2E211950117643375 Affinity Capture-MS
UBR5KPNA111003412011095 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
UBR5KPNA111950112011095 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
UBR5PGR11126012011095 Reconstituted Complex
UBR5PGR11950112011095 Reconstituted Complex
UBR5PMS111950117148452 Affinity Capture-Western
UBR5PMS111139117148452 Affinity Capture-Western
UBR5PMS211950117148452 Affinity Capture-MS
UBR5PMS211140417148452 Affinity Capture-MS
UBR5MAPK111158012594221 Affinity Capture-Western; Biochemical Activity
UBR5MAPK111950112594221 Affinity Capture-Western; Biochemical Activity
UBR5MAPK311950112594221 Affinity Capture-Western
UBR5MAPK311158112594221 Affinity Capture-Western
UBR5TCEA111277917643375 Affinity Capture-MS
UBR5TCEA111950117643375 Affinity Capture-MS
UBR5RECQL511479719270065 Affinity Capture-MS
UBR5RECQL511950119270065 Affinity Capture-MS
UBR5MAGED111487917353931 Affinity Capture-MS
UBR5MAGED111950117353931 Affinity Capture-MS
UBR5MCRS111571017353931 Affinity Capture-MS
UBR5MCRS111950117353931 Affinity Capture-MS
UBR5CIB111577412011095 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
UBR5CIB111950112011095 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
UBR5TOPBP111625611714696 Affinity Capture-Western; Biochemical Activity; Two-hybrid
UBR5TOPBP111950111714696 Affinity Capture-Western; Biochemical Activity; Two-hybrid
UBR5USP4911950119615732 Affinity Capture-MS
UBR5USP4911738219615732 Affinity Capture-MS
UBR5PAIP211950116601676 Affinity Capture-Western
UBR5PAIP211940416601676 Affinity Capture-Western
WDR48UBR512164919615732 Affinity Capture-MS
WDR48UBR511950119615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1918040
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-6559'