Annotation Details for PPME1

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Basic Information Top

Gene Symbol:	PPME1 ( FLJ22226,PME-1 )
Gene Full Name:	protein phosphatase methylesterase 1
Band:	11q13.4
Quick Links	Entrez ID:51400; OMIM: 611117; Uniprot ID:PPME1_HUMAN; ENSEMBL ID: ENSG00000214517; HGNC ID: 30178
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

AlzGene, PDGene and SZGene

Gene Ontology

Cellular Component:1 results
Molecular Function:8 results
Biological Process:3 results

GO ID	Evidence	Qualifier	GO_term	References
GO:0005654	TAS	-	nucleoplasm	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0004864	TAS	-	protein phosphatase inhibitor activity	10318862
GO:0019888	TAS	-	protein phosphatase regulator activity	10318862
GO:0019901	IEA	-	protein kinase binding	-
GO:0019903	IDA	-	protein phosphatase binding	10318862
GO:0045296	IDA	-	cadherin binding	25468996
GO:0051721	IDA	-	protein phosphatase 2A binding	10318862
GO:0051722	IDA	-	protein C-terminal methylesterase activity	10318862
GO:0051722	TAS	-	protein C-terminal methylesterase activity	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0000086	TAS	-	G2/M transition of mitotic cell cycle	-
GO:0006482	IDA	-	protein demethylation	10318862
GO:0043086	IEA	-	negative regulation of catalytic activity	-

Protein-Protein Interaction

BioGRID:4 results
BIND:0 results
HPRD:0 results

Gene Symbol	Interactant	Interaction ID	References	Description
PPME1	PPP2CA	111507	18782753	Affinity Capture-MS
PPME1	PPP2CA	119524	18782753	Affinity Capture-MS
PPME1	PPP2R1A	119524	18782753	Affinity Capture-MS
PPME1	PPP2R1A	111510	18782753	Affinity Capture-MS

AlzGene, PDGene and SZGene

Animal Model

Mouse:1 results
Fruit Fly:0 results

MGI ID: MGI:1919840
Data Attributes: MGI curated and HomoloGene calculated